EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
3.1.4.11 | chlorpromazine | stimulates at pH 5.5 | Sus scrofa | |
3.1.4.11 | Cinchocaine | stimulates at pH 5.5 | Sus scrofa |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.1.4.11 | CaCl2 | above 0.4 mM, pH 7.0 | Sus scrofa | |
3.1.4.11 | chlorpromazine | at pH 7.0 | Sus scrofa | |
3.1.4.11 | Cinchocaine | at pH 7.0 | Sus scrofa | |
3.1.4.11 | MgCl2 | above 0.4 mM, pH 7.0 | Sus scrofa |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
3.1.4.11 | CaCl2 | stimulates at pH 5.5, pH dependent | Sus scrofa | |
3.1.4.11 | K+ | stimulates at pH 5.5 | Sus scrofa | |
3.1.4.11 | MgCl2 | stimulates at pH 5.5, but less active than CaCl2, pH dependent | Sus scrofa |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.1.4.11 | Sus scrofa | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.1.4.11 | lymphocyte | from mesenteric lymph nodes | Sus scrofa | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
3.1.4.11 | additional information | - |
activity at pH 7.0 (and 0.4 mM CaCl2) is decreased by agents, such as salts and lipophilic cations, which tend to neutralize the negative charge of phosphatidylinositol. At pH 5.5 these agents slightly stimulate activity | Sus scrofa |
3.1.4.11 | 0.025 | - |
pH 7.3, pellet | Sus scrofa |
3.1.4.11 | 0.034 | - |
pH 5.4, pellet | Sus scrofa |
3.1.4.11 | 0.082 | - |
pH 7.3, cell pellet | Sus scrofa |
3.1.4.11 | 0.088 | - |
pH 5.4, cell pellet | Sus scrofa |
3.1.4.11 | 0.26 | - |
pH 7.3, supernatant (soluble) | Sus scrofa |
3.1.4.11 | 0.28 | - |
pH 5.4, supernatant (soluble) | Sus scrofa |
EC Number | Storage Stability | Organism |
---|---|---|
3.1.4.11 | -20°C, stable for several month | Sus scrofa |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.4.11 | additional information | no activity is detectable towards either phosphatidylcholine or phosphatidylethanolamine | Sus scrofa | ? | - |
? | |
3.1.4.11 | phosphatidylinositol + H2O | - |
Sus scrofa | 1,2-diacylglycerol + 1D-myo-inositol 1-phosphate | 1D-myo-inositol 1,2-cyclic phosphate is also formed | ? |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
3.1.4.11 | 5.4 | 5.6 | 5.4-5.6 and 7.0-7.3 | Sus scrofa |
3.1.4.11 | 5.6 | - |
assay at | Sus scrofa |
3.1.4.11 | 7 | 7.3 | 5.4-5.6 and 7.0-7.3 | Sus scrofa |
3.1.4.11 | 7.1 | - |
assay at | Sus scrofa |
EC Number | pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|---|
3.1.4.11 | 4.5 | 7.5 | - |
Sus scrofa |