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Literature summary extracted from

  • Mauco, G.; Chap, H.; Douste-Blazy, L.
    Characterization and properties of a phosphatidylinositol phosphodiesterase (phospholipase C) from platelet cytosol (1979), FEBS Lett., 100, 367-370.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.4.11 Ca2+ at high concentrations Homo sapiens
3.1.4.11 EDTA 2 mM, 70% inhibition Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.4.11 cytosol
-
 Homo sapiens 5829
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.1.4.11 Ca2+ optimal concentrations are 0.3 mM and 8 mM using 0.2 mM and 0.4 mM phosphatidylinositol Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.1.4.11 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.4.11 blood platelet
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.4.11 arachidonoyl-phosphatidylinositol + H2O
-
 Homo sapiens 1,2-diarachidonoyl-sn-glycerol + 1D-myo-inositol 1-phosphate
-
 ?
3.1.4.11 phosphatidylinositol + H2O
-
 Homo sapiens 1D-myo-inositol-1-phosphate + diacylglycerol in vitro 1D-myo-inositol-1,2-cyclic phosphate is also formed ?

Synonyms

EC Number Synonyms Comment Organism
3.1.4.11 phosphatidylinositol phosphodiesterase
-
 Homo sapiens
3.1.4.11 phospholipase C
-
 Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.1.4.11 6
-
-
 Homo sapiens

pH Range

EC Number pH Minimum pH Maximum Comment Organism
3.1.4.11 6 7
-
 Homo sapiens