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Literature summary extracted from
- Phospholipase C and diacylglycerol lipase activities associated with plasma membranes of chromaffin cells isolated from bovine adrenal medulla (1986), Biochim. Biophys. Acta, 877, 372-379.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.1.4.11 | additional information | enzyme is not inhibited by 1.7 mM p-bromophenacylbromide | Bos taurus |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.1.4.11 | Ca2+ | dependend | Bos taurus |  |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.4.11 | additional information | Bos taurus | enzyme is phosphatidylinositol-specific and does not act on phosphatidylethanolamine and phosphatidylcholine | ? | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.1.4.11 | Bos taurus | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.1.4.11 | adrenal medulla | bovine adrenal chromaffin cells | Bos taurus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.4.11 | additional information | enzyme is phosphatidylinositol-specific and does not act on phosphatidylethanolamine and phosphatidylcholine | Bos taurus | ? | - |
? | |
| 3.1.4.11 | phosphatidylinositol + H2O | enzyme is phosphatidylinositol specific | Bos taurus | 1D-myo-inositol 1-phosphate + diacylglycerol | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.1.4.11 | endogenous phospholipase C | - |
Bos taurus |
| 3.1.4.11 | phospholipase C | - |
Bos taurus |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 3.1.4.11 | 37 | - |
assay at | Bos taurus |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.1.4.11 | 7.4 | - |
assay at | Bos taurus |
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Release 2023.1 (January 2023)
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