Literature summary extracted from

Boll, M.; Laempe, D.; Eisenreich, W.; Bachers, A.; Mittelberger, T.; Heinze, J.; Fuchs, G.
Nonaromatic products from anoxic conversion of benzoyl-CoA with benzoyl-CoA reductase and cyclohexa-1,5-diene-1-carbonyl-CoA hydratase (2000), J. Biol. Chem., 275, 21889-21895.

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.3.7.8	Thauera aromatica	-	-	-
4.2.1.100	Thauera aromatica	-	-	-

Reaction

EC Number	Reaction	Comment	Organism	Reaction ID
1.3.7.8	cyclohexa-1,5-diene-1-carbonyl-CoA + oxidized ferredoxin + 2 ADP + 2 phosphate = benzoyl-CoA + reduced ferredoxin + 2 ATP + 2 H2O	Birch-like reduction with base-catalyzed rearrangement to 1,5-diene	Thauera aromatica	a

Specific Activity [micromol/min/mg]

EC Number	Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
4.2.1.100	110	-	reversible reaction with 6-hydroxycyclohex-1-ene-1-carboxyl-CoA as substrat	Thauera aromatica

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.3.7.8	benzoyl-CoA + reduced ferredoxin + ATP	-	Thauera aromatica	cyclohexa-1,5-diene-1-carbonyl-CoA + ferredoxin + ADP + phosphate	-	?
1.3.7.8	additional information	reduction of aromatic ring requires 2 mol of ATP per mol of benzoyl-CoA	Thauera aromatica	?	-	?
4.2.1.100	cyclohex-1-ene-1-carbonyl-CoA + H2O	-	Thauera aromatica	2-hydroxycyclohexane-1-carbonyl-CoA	-	?
4.2.1.100	cyclohexa-2,5-diene-1-carbonyl-CoA + H2O	only when dithionite is used as an artificial electron donor	Thauera aromatica	6-hydroxycyclohex-2-ene-1-carbonyl-CoA	-	?

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)