Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Gracy, R.W.; Tilley, B.E.
    Phosphoglucose isomerase of human erythrocytes and cardiac tissue (1975), Methods Enzymol., 41B, 392-400.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
5.3.1.9 0.071
-
 fructose 6-phosphate
-
 Homo sapiens
5.3.1.9 0.12
-
 fructose 6-phosphate glucose 6-phosphate Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
5.3.1.9 63000
-
 2 * 63000, sedimentation velocity ultracentrifugation of enzyme dissociated in 6 M guanidine/HCl Homo sapiens
5.3.1.9 132000
-
 sedimentation velocity ultracentrifugation Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
5.3.1.9 Homo sapiens
-
-
-

Oxidation Stability

EC Number Oxidation Stability Organism
5.3.1.9 susceptible to oxidation of sulfhydryl groups yielding multiple electrophoretic forms with catalytic activity Homo sapiens

Purification (Commentary)

EC Number Purification (Comment) Organism
5.3.1.9
-
 Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
5.3.1.9 erythrocyte
-
 Homo sapiens
-
5.3.1.9 heart
-
 Homo sapiens
-

Storage Stability

EC Number Storage Stability Organism
5.3.1.9 best storage conditions: as crystalline suspension or precipitate in 0.70 saturated ammonium sulfate containing 50 mM triethanolamine buffer, pH 8.3, 1 mM EDTA, 1 mM dithiothreitol Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.3.1.9 Fructose 6-phosphate r Homo sapiens Glucose 6-phosphate
-
 ?
5.3.1.9 Glucose 6-phosphate r Homo sapiens Fructose 6-phosphate
-
 ?

Subunits

EC Number Subunits Comment Organism
5.3.1.9 dimer 2 * 63000, sedimentation velocity ultracentrifugation of enzyme dissociated in 6 M guanidine/HCl Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
5.3.1.9 8.3
-
-
 Homo sapiens

pH Range

EC Number pH Minimum pH Maximum Comment Organism
5.3.1.9 7 10 about 50% of maximal activity at pH 7 and at pH 10 Homo sapiens