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Literature summary extracted from

  • Jaeken, J.; Pirard, M.; Adamowicz, M.; Pronicka, E.; van Schaftingen, E.
    Inhibition of phosphomannose isomerase by fructose 1-phosphate: an explanation for defective N-glycosylation in hereditary fructose intolerance (1996), Pediatr. Res., 40, 764-766.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
5.3.1.8 fructose 1-phosphate competitive Homo sapiens
5.4.2.8 fructose 1-phosphate
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5.3.1.8 D-Fructose 6-phosphate Homo sapiens first enzyme of the N-glycosylation pathway ?
-
 ?
5.4.2.8 D-mannose 6-phosphate Homo sapiens first enzyme of the N-glycosylation pathway D-mannose 1-phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
5.3.1.8 Homo sapiens
-
-
-
5.4.2.8 Homo sapiens
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.3.1.8 D-Fructose 6-phosphate first enzyme of the N-glycosylation pathway Homo sapiens ?
-
 ?
5.3.1.8 D-Mannose 6-phosphate
-
 Homo sapiens D-Fructose 6-phosphate
-
 ?
5.4.2.8 D-Mannose 1-phosphate
-
 Homo sapiens D-Mannose 6-phosphate
-
 ?
5.4.2.8 D-mannose 6-phosphate first enzyme of the N-glycosylation pathway Homo sapiens D-mannose 1-phosphate
-
 ?