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Literature summary extracted from

  • Wells, T.N.C.; Payton, M.A.; Proudfoot, A.E.I.
    Inhibition of phosphomannose isomerase by mercury ions (1994), Biochemistry, 33, 7641-7646.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
5.3.1.8 Hg2+ partial noncompetitive inhibition with mannose 6-phosphate as substrate. In addition to the inhibition at rapid equilibrium, inactivation occurs in a two-step process, proceeding via an intermediate complex. The rate of the irreversible inactivation can be slowed by the addition of the substrate mannose 6-phosphate Candida albicans
5.3.1.8 Hg2+
-
Saccharomyces cerevisiae

Organism

EC Number Organism UniProt Comment Textmining
5.3.1.8 Candida albicans
-
-
-
5.3.1.8 Homo sapiens
-
-
-
5.3.1.8 Saccharomyces cerevisiae
-
-
-
5.3.1.8 Sus scrofa
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.3.1.8 D-Mannose 6-phosphate
-
Homo sapiens D-Fructose 6-phosphate
-
?
5.3.1.8 D-Mannose 6-phosphate
-
Sus scrofa D-Fructose 6-phosphate
-
?
5.3.1.8 D-Mannose 6-phosphate
-
Saccharomyces cerevisiae D-Fructose 6-phosphate
-
?
5.3.1.8 D-Mannose 6-phosphate
-
Candida albicans D-Fructose 6-phosphate
-
?