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Literature summary extracted from

  • Gerlo, E.; Freist, W.; Charlier, J.
    Arginyl-tRNA synthetase from Escherichia coli K12: specificity with regard to ATP analogs and their magnesium complexes (1982), Hoppe-Seyler's Z. Physiol. Chem., 363, 365-373.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
6.1.1.19 2'-methoxyadenosine 5'-triphosphate
-
 Escherichia coli
6.1.1.19 2-Aminopurine riboside 5'-triphosphate
-
 Escherichia coli
6.1.1.19 6-N-Benzyladenosine 5'-triphosphate
-
 Escherichia coli
6.1.1.19 8-azidoadenosine 5'-triphosphate
-
 Escherichia coli
6.1.1.19 8-bromoadenosine 5'-triphosphate
-
 Escherichia coli
6.1.1.19 purine riboside
-
 Escherichia coli

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
6.1.1.19 0.1
-
 3'-Methoxyadenosine 5'-triphosphate aminoacylation Escherichia coli
6.1.1.19 0.15
-
 Arg 2'-deoxyadenosine 5'-triphosphate, , aminoacylation Escherichia coli
6.1.1.19 0.2
-
 tubercidin 5'-triphosphate tubercidine 5'-triphosphate, , aminoacylation Escherichia coli
6.1.1.19 0.4
-
 tubercidin 5'-triphosphate 3'-methoxyadenosine 5'-triphosphate, , NTP-diphosphate exchange Escherichia coli
6.1.1.19 0.5
-
 3'-Deoxyadenosine 5'-triphosphate aminoacylation Escherichia coli
6.1.1.19 1.2
-
 ATP aminoacylation Escherichia coli
6.1.1.19 1.3
-
 2-Chloroadenosine 5'-triphosphate NTP-diphosphate exchange Escherichia coli
6.1.1.19 1.5
-
 2'-deoxyadenosine 5'-triphosphate NTP-diphosphate exchange Escherichia coli
6.1.1.19 1.9
-
 ATP NTP-diphosphate exchange Escherichia coli
6.1.1.19 2.5
-
 2-Chloroadenosine 5'-triphosphate aminoacylation Escherichia coli
6.1.1.19 3
-
 8-azaadenosine 5'-triphosphate aminoacylation Escherichia coli
6.1.1.19 3.3
-
 8-azaadenosine 5'-triphosphate NTP-diphosphate exchange Escherichia coli

Organism

EC Number Organism UniProt Comment Textmining
6.1.1.19 Escherichia coli
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.1.1.19 2'-deoxyadenosine 5'-triphosphate + L-arginine + tRNAArg
-
 Escherichia coli 2'-deoxyadenosine 5'-monophosphate + diphosphate + L-arginyl-tRNAArg
-
 ?
6.1.1.19 2-chloroadenosine 5'-triphosphate + L-arginine + tRNAArg
-
 Escherichia coli 2-chloroadenosine 5'-monophosphate + diphosphate + L-arginyl-tRNAArg
-
 ?
6.1.1.19 3'-deoxyadenosine 5'-triphosphate + L-arginine + tRNAArg
-
 Escherichia coli 3'-deoxyadenosine 5'-monophosphate + diphosphate + L-arginyl-tRNAArg
-
 ?
6.1.1.19 3'-methoxyadenosine 5'-triphosphate + L-arginine + tRNAArg
-
 Escherichia coli 3'-methoxyadenosine 5'-monophosphate + diphosphate + L-arginyl-tRNAArg
-
 ?
6.1.1.19 8-azaadenosine 5'-triphosphate + L-arginine + tRNAArg
-
 Escherichia coli 8-azaadenosine 5'-monophosphate + diphosphate + L-arginyl-tRNAArg
-
 ?
6.1.1.19 ATP + L-arginine + tRNAArg
-
 Escherichia coli AMP + diphosphate + L-arginyl-tRNAArg
-
 ?
6.1.1.19 additional information arginine-dependent ATP-diphosphate exchange Escherichia coli ?
-
 ?
6.1.1.19 tubercidin 5'-triphosphate + L-arginine + tRNAArg
-
 Escherichia coli tubercidin 5'-monophosphate + diphosphate + L-arginyl-tRNAArg
-
 ?