Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Contractor, S.F.; Shane, B.
    Purification and characterization of lysosomal -glucuronidase from human placenta (1972), Biochem. J., 128, 11-18.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.2.1.31 bovine serum albumin activation Homo sapiens
3.2.1.31 Plasma serum acivation Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.2.1.31 inhibitor heat stable, competetive, in plasma Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.2.1.31 0.018 3.08 phenolphthalein beta-D-glucuronide dependency on pH Homo sapiens
3.2.1.31 0.041 1.3 4-methylumbelliferyl-beta-D-glucuronide
-
 Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.2.1.31 lysosome
-
 Homo sapiens 5764
-
3.2.1.31 microsome
-
 Homo sapiens
-
-

Organism

EC Number Organism UniProt Comment Textmining
3.2.1.31 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.2.1.31
-
 Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.2.1.31 placenta
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.2.1.31 additional information
-
-
 Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.2.1.31 phenolphthalein beta-D-glucuronide + H2O
-
 Homo sapiens phenolphthalein + D-glucuronic acid
-
 ?

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
3.2.1.31 70
-
 lysosomal form: 60 min, 80% activity, plasma enzyme: 15 min, 0% activity Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.2.1.31 3
-
 substrate 4-methylumbelliferyl-beta-D-glucuronide Homo sapiens
3.2.1.31 5
-
-
 Homo sapiens