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Literature summary extracted from
- Phosphoramidates. V. probable identity of rat liver microsomal glucose 6-phosphatase, phosphoramidase, and phosphoramidate-hexose phosphotransferase (1969), Biochemistry, 8, 1748-1755.
General Stability
| EC Number | General Stability | Organism |
|---|---|---|
| 3.9.1.1 | enzyme is active for more than 5 h, shows activity even at 0°C | Rattus norvegicus |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.9.1.1 | molybdate | - |
Rattus norvegicus |  |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.9.1.1 | 13 | - |
Phosphoramidate | - |
Rattus norvegicus | |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 3.9.1.1 | microsome | - |
Rattus norvegicus | - |
- |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.9.1.1 | Rattus norvegicus | - |
- |
- |
Reaction
| EC Number | Reaction | Comment | Organism | Reaction ID |
|---|---|---|---|---|
| 3.9.1.1 | N-phosphocreatine + H2O = creatine + phosphate | reaction mechanism | Rattus norvegicus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.9.1.1 | kidney | - |
Rattus norvegicus | - |
| 3.9.1.1 | liver | - |
Rattus norvegicus | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 3.9.1.1 | 0.16 | - |
substrate phosphoramidate, enzyme source kidney microsomes | Rattus norvegicus |
| 3.9.1.1 | 0.181 | - |
substrate phosphoramidate, enzyme source liver microsomes | Rattus norvegicus |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.9.1.1 | phosphoramidate + H2O | - |
Rattus norvegicus | NH4+ + phosphate | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.9.1.1 | More | - |
- |
pH Stability
| EC Number | pH Stability | pH Stability Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.9.1.1 | 5 | - |
pretreatment with pH 5.0 reduces activity 25fold | Rattus norvegicus |
| 3.9.1.1 | 9.7 | - |
pretreatment with pH 9.7 increases activity 1.4fold, KM decreases 5.7fold | Rattus norvegicus |
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Release 2023.1 (January 2023)
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