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Literature summary extracted from

  • Gibbons, B.H.; Tang, W.J.Y.; Gibbons, I.R.
    Organic anions stabilize the reactivated motility of sperm flagella and the latency of dynein 1 ATPase activity (1985), J. Cell Biol., 101, 1281-1287.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
5.6.1.2 acetate 2fold activation, maximum between 0.5 and 0.7 M Tripneustes gratilla
5.6.1.2 Cl- more than 15fold activation between 0 and 1.0 M Tripneustes gratilla
5.6.1.2 Lactate 2fold activation, maximum between 0.5 and 0.7 M Tripneustes gratilla
5.6.1.2 succinate 2fold activation, maximum between 0.5 and 0.7 M Tripneustes gratilla

Inhibitors

EC Number Inhibitors Comment Organism Structure
5.6.1.2 VO43- 50% inhibition at 0.00031 mM vanadate plus 0.15 M KCl, 0.0001 mM vanadate plus 0.20 M K-acetate, 0.00021 mM vanadate plus 0.20 M K-lactate, 0.00011 mM vanadate plus 0.20 M K2-succinate Tripneustes gratilla

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5.6.1.2 ATP + H2O + a dynein associated with a microtubule at position n Tripneustes gratilla
-
 ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
5.6.1.2 Tripneustes gratilla
-
 sea urchin
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
5.6.1.2 semen
-
 Tripneustes gratilla
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.6.1.2 ATP + H2O + a dynein associated with a microtubule at position n
-
 Tripneustes gratilla ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
 ?