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Literature summary extracted from
- Vertebrate unconventional myosins (1996), J. Biol. Chem., 271, 16431-16434.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 5.6.1.8 | actin | - |
Mus musculus |  |
| 5.6.1.8 | actin | - |
Homo sapiens | |
| 5.6.1.8 | actin | - |
Rattus norvegicus | |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 5.6.1.8 | cytoplasm | punctate distribution | Homo sapiens | 5737 | - |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 5.6.1.8 | ATP + H2O + myosin bound to actin filament at position n | Mus musculus | - |
ADP + phosphate + myosin bound to actin filament at position n+1 | - |
? | |
| 5.6.1.8 | ATP + H2O + myosin bound to actin filament at position n | Homo sapiens | - |
ADP + phosphate + myosin bound to actin filament at position n+1 | - |
? | |
| 5.6.1.8 | ATP + H2O + myosin bound to actin filament at position n | Rattus norvegicus | - |
ADP + phosphate + myosin bound to actin filament at position n+1 | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 5.6.1.8 | Homo sapiens | - |
- |
- |
| 5.6.1.8 | Mus musculus | - |
mouse | - |
| 5.6.1.8 | Rattus norvegicus | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 5.6.1.8 | cochlea | myosin-VIIa, exclusively expressed by sensory hair cells | Mus musculus | - |
| 5.6.1.8 | retina | myosin-VIIa, exclusively expressed by pigmented epithelial cells | Rattus norvegicus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 5.6.1.8 | ATP + H2O + myosin bound to actin filament at position n | - |
Mus musculus | ADP + phosphate + myosin bound to actin filament at position n+1 | - |
? | |
| 5.6.1.8 | ATP + H2O + myosin bound to actin filament at position n | - |
Homo sapiens | ADP + phosphate + myosin bound to actin filament at position n+1 | - |
? | |
| 5.6.1.8 | ATP + H2O + myosin bound to actin filament at position n | - |
Rattus norvegicus | ADP + phosphate + myosin bound to actin filament at position n+1 | - |
? | |
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Release 2023.1 (January 2023)
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