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Literature summary extracted from

  • Takeda, K.; Ushimaru, M.; Fukushima, Y.; Kawamura, M.
    Characterization of a P-type copper-stimulated ATPase from mouse liver (1999), J. Membr. Biol., 170, 13-16.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
7.2.2.9 dithioerythritol GSH, dithiothreitol or dithioerythritol are required for activity Mus musculus
7.2.2.9 dithiothreitol GSH, dithiothreitol or dithioerythritol are required for activity Mus musculus
7.2.2.9 GSH GSH, dithiothreitol or dithioerythritol are required for activity Mus musculus

Inhibitors

EC Number Inhibitors Comment Organism Structure
7.2.2.9 NaBr 240 mM, reduces activity Mus musculus
7.2.2.9 NaNO3 240 mM, reduces activity Mus musculus
7.2.2.9 PCMB
-
 Mus musculus
7.2.2.9 vanadate
-
 Mus musculus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
7.2.2.9 microsome
-
 Mus musculus
-
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
7.2.2.9 Iron used instead of copper also stimulates ATPase and phosphorylation Mus musculus
7.2.2.9 KCl ATPase activity increases with increasing salt concentration Mus musculus
7.2.2.9 NaCl ATPase activity increases with increasing salt concentration Mus musculus
7.2.2.9 NaSCN activates Mus musculus

Organism

EC Number Organism UniProt Comment Textmining
7.2.2.9 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
7.2.2.9 liver
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
7.2.2.9 ATP + H2O + Cu2+/in
-
 Mus musculus ADP + phosphate + Cu2+/out
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
7.2.2.9 5
-
-
 Mus musculus