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Literature summary extracted from
- Studies of bovine seminal fluid nucleotide pyrophosphatase (1980), Arch. Biochem. Biophys., 202, 396-404.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.6.1.9 | NaCl | maximal activity at 20 mM, ionic strength affects activity below 10 mM | Bos taurus |  |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.6.1.9 | adenosine | competitive inhibition, Ki: 2.7 mM | Bos taurus | |
| 3.6.1.9 | adenylic acid | competitive inhibition, Ki: 0.036 mM | Bos taurus | |
| 3.6.1.9 | Sodium diphosphate | competitive inhibition, Ki: 0.41 mM | Bos taurus | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.6.1.9 | 0.005 | - |
FAD | - |
Bos taurus | |
| 3.6.1.9 | 0.007 | - |
3-Aminopyridine adenine dinucleotide | - |
Bos taurus | |
| 3.6.1.9 | 0.009 | - |
NAD+ | - |
Bos taurus | |
| 3.6.1.9 | 0.009 | - |
nicotinamide 1,N6-ethenoadenine dinucleotide | - |
Bos taurus | |
| 3.6.1.9 | 0.011 | - |
adenosine diphosphoribose | - |
Bos taurus | |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.6.1.9 | ADP-ribose + H2O | Bos taurus | - |
AMP + phosphoribose | - |
? | |
| 3.6.1.9 | FAD + H2O | Bos taurus | - |
FMN + AMP | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.6.1.9 | Bos taurus | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.6.1.9 | partial | Bos taurus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.6.1.9 | semen | - |
Bos taurus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.6.1.9 | 3-aminopyridine adenine dinucleotide + H2O | - |
Bos taurus | 3-aminopyridine riboside 5'-phosphate + 5'-AMP | - |
? | |
| 3.6.1.9 | ADP-ribose + H2O | - |
Bos taurus | AMP + phosphoribose | - |
? | |
| 3.6.1.9 | FAD + H2O | - |
Bos taurus | FMN + AMP | - |
? | |
| 3.6.1.9 | NAD+ + H2O | - |
Bos taurus | NMN + AMP | - |
? | |
| 3.6.1.9 | nicotinamide 1,N6-ethenoadenine dinucleotide + H2O | - |
Bos taurus | NMN + N6-ethenoadenosine 5'-phosphate | - |
? | |
Temperature Stability [°C]
| EC Number | Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 3.6.1.9 | 41 | - |
denaturation above | Bos taurus |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.6.1.9 | 9 | - |
- |
Bos taurus |
Ki Value [mM]
| EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.6.1.9 | 0.036 | - |
adenylic acid | competitive inhibition | Bos taurus | |
| 3.6.1.9 | 2.7 | - |
adenosine | competitive inhibition | Bos taurus | |
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Release 2023.1 (January 2023)
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