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Literature summary extracted from

  • Kinoshita, S.; Negoro, S.; Muramatso, M.; Bisaria, V.S.; Sawada, S.; Okada, H.
    6-Aminohexanoic acid cyclic dimer hydrolase. A new cyclic amide hydrolase produced by Achromobacter guttatus KI72 (1977), Eur. J. Biochem., 80, 489-495.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.5.2.12 diisopropylphosphofluoridate 1 mM Achromobacter guttatus
3.5.2.12 p-chloromercuribenzoate 10 mM Achromobacter guttatus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.5.2.12 55000
-
 2 * 55000, SDS-PAGE Achromobacter guttatus
3.5.2.12 110000
-
 gel filtration Achromobacter guttatus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.5.2.12 1,8-diazacyclotetradecane-2,9-dione + H2O Achromobacter guttatus
-
 N-(6-aminohexanoyl)-6-aminohexanoate
-
 ?
3.5.2.12 1,8-diazacyclotetradecane-2,9-dione + H2O Achromobacter guttatus KI72
-
 N-(6-aminohexanoyl)-6-aminohexanoate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.5.2.12 Achromobacter guttatus
-
 KI72
-
3.5.2.12 Achromobacter guttatus KI72
-
 KI72
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.5.2.12
-
 Achromobacter guttatus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.5.2.12 1,8-diazacyclotetradecane-2,9-dione + H2O
-
 Achromobacter guttatus N-(6-aminohexanoyl)-6-aminohexanoate
-
 ?
3.5.2.12 1,8-diazacyclotetradecane-2,9-dione + H2O i.e. 6-aminohexanoic acid cyclic dimer Achromobacter guttatus N-(6-aminohexanoyl)-6-aminohexanoate
-
 ?
3.5.2.12 1,8-diazacyclotetradecane-2,9-dione + H2O
-
 Achromobacter guttatus KI72 N-(6-aminohexanoyl)-6-aminohexanoate
-
 ?
3.5.2.12 1,8-diazacyclotetradecane-2,9-dione + H2O i.e. 6-aminohexanoic acid cyclic dimer Achromobacter guttatus KI72 N-(6-aminohexanoyl)-6-aminohexanoate
-
 ?

Subunits

EC Number Subunits Comment Organism
3.5.2.12 dimer 2 * 55000, SDS-PAGE Achromobacter guttatus

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.5.2.12 33
-
-
 Achromobacter guttatus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.5.2.12 7.3
-
-
 Achromobacter guttatus

pH Range

EC Number pH Minimum pH Maximum Comment Organism
3.5.2.12 5.5 8.5
-
 Achromobacter guttatus