BRENDA - Enzyme Database show

Nicotinamide deaminase from mammalian liver

Petrack, B.; Greengard, P.; Craston, N.; Sheppy, F.; J. Biol. Chem. 240, 1725-1730 (1965)

Data extracted from this reference:

KM Value [mM]
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
3.5.1.19
50
-
nicotinamide
-
Rattus norvegicus
Localization
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
3.5.1.19
microsome
-
Oryctolagus cuniculus
-
-
3.5.1.19
microsome
-
Rattus norvegicus
-
-
3.5.1.19
mitochondrion
-
Rattus norvegicus
5739
-
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
3.5.1.19
Oryctolagus cuniculus
-
-
-
3.5.1.19
Rattus norvegicus
-
-
-
Purification (Commentary)
EC Number
Commentary
Organism
3.5.1.19
-
Oryctolagus cuniculus
3.5.1.19
-
Rattus norvegicus
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
3.5.1.19
liver
-
Rattus norvegicus
-
3.5.1.19
liver
-
Oryctolagus cuniculus
-
Specific Activity [micromol/min/mg]
EC Number
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
3.5.1.19
additional information
-
-
Oryctolagus cuniculus
3.5.1.19
additional information
-
-
Rattus norvegicus
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.5.1.19
nicotinamide + H2O
-
246568
Rattus norvegicus
nicotinate + NH3
-
-
-
?
3.5.1.19
nicotinamide + H2O
-
246568
Oryctolagus cuniculus
nicotinate + NH3
-
-
-
?
pH Optimum
EC Number
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
3.5.1.19
9
10
-
Rattus norvegicus
pH Range
EC Number
pH Minimum
pH Maximum
Commentary
Organism
3.5.1.19
7
11
pH 7.0: about 35% of maximal activity, pH 11.0: about 30% of maximal activity
Rattus norvegicus
KM Value [mM] (protein specific)
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
3.5.1.19
50
-
nicotinamide
-
Rattus norvegicus
Localization (protein specific)
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
3.5.1.19
microsome
-
Oryctolagus cuniculus
-
-
3.5.1.19
microsome
-
Rattus norvegicus
-
-
3.5.1.19
mitochondrion
-
Rattus norvegicus
5739
-
Purification (Commentary) (protein specific)
EC Number
Commentary
Organism
3.5.1.19
-
Oryctolagus cuniculus
3.5.1.19
-
Rattus norvegicus
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
3.5.1.19
liver
-
Rattus norvegicus
-
3.5.1.19
liver
-
Oryctolagus cuniculus
-
Specific Activity [micromol/min/mg] (protein specific)
EC Number
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
3.5.1.19
additional information
-
-
Oryctolagus cuniculus
3.5.1.19
additional information
-
-
Rattus norvegicus
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.5.1.19
nicotinamide + H2O
-
246568
Rattus norvegicus
nicotinate + NH3
-
-
-
?
3.5.1.19
nicotinamide + H2O
-
246568
Oryctolagus cuniculus
nicotinate + NH3
-
-
-
?
pH Optimum (protein specific)
EC Number
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
3.5.1.19
9
10
-
Rattus norvegicus
pH Range (protein specific)
EC Number
pH Minimum
pH Maximum
Commentary
Organism
3.5.1.19
7
11
pH 7.0: about 35% of maximal activity, pH 11.0: about 30% of maximal activity
Rattus norvegicus