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Literature summary extracted from

  • Munford, R.S.; Erwin, A.L.
    Eukaryotic lipopolysaccharide deacylation enzyme (1992), Methods Enzymol., 209, 485-492.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.1.1.77 Triton X-100 required Homo sapiens

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.1.1.77 in BHK 570 cells Homo sapiens

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.1.1.77 Ca2+ 5 mM enhances activity by 30-50% at low substrate concentration, inhibitory at high substrate concentration Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.1.77 3-(acyloxy)acyl group of bacterial toxin Homo sapiens detoxification of LPS 3-hydroxyacyl group of bacterial toxin + a fatty acid
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.77 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.1.77
-
 Homo sapiens

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.1.1.77 0.000005
-
 cell lysate Homo sapiens
3.1.1.77 1.555
-
 purified enzyme Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.77 3-(acyloxy)acyl group of bacterial toxin detoxification of LPS Homo sapiens 3-hydroxyacyl group of bacterial toxin + a fatty acid
-
 ?
3.1.1.77 3-(acyloxy)acyl group of bacterial toxin + H2O
-
 Homo sapiens 3-hydroxyacyl group of bacterial toxin + a fatty acid
-
 ?