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Literature summary extracted from

  • Mc Dermott, C.M.; Cullor, J.S.; Fenwick, B.W.
    Intracellular and extracellular enzymatic deacylation of bacterial endotoxin during localized inflammation induced by Escherichia coli (1991), Infect. Immun., 59, 487-485.
No PubMed abstract available

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.1.77 3-(acyloxy)acyl group of bacterial toxin Homo sapiens detoxification of LPS 3-hydroxyacyl group of bacterial toxin + a fatty acid
-
 ?
3.1.1.77 3-(acyloxy)acyl group of bacterial toxin Bos taurus detoxification of LPS 3-hydroxyacyl group of bacterial toxin + a fatty acid
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.77 Bos taurus
-
-
-
3.1.1.77 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.1.77 HL-60 cell
-
 Homo sapiens
-
3.1.1.77 milk cell free Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.77 3-(acyloxy)acyl group of bacterial toxin detoxification of LPS Homo sapiens 3-hydroxyacyl group of bacterial toxin + a fatty acid
-
 ?
3.1.1.77 3-(acyloxy)acyl group of bacterial toxin detoxification of LPS Bos taurus 3-hydroxyacyl group of bacterial toxin + a fatty acid
-
 ?
3.1.1.77 3-(acyloxy)acyl group of bacterial toxin + H2O
-
 Homo sapiens 3-hydroxyacyl group of bacterial toxin + a fatty acid
-
 ?
3.1.1.77 3-(acyloxy)acyl group of bacterial toxin + H2O
-
 Bos taurus 3-hydroxyacyl group of bacterial toxin + a fatty acid
-
 ?

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
3.1.1.77 80
-
 10 min causes complete inactivation Bos taurus

pH Range

EC Number pH Minimum pH Maximum Comment Organism
3.1.1.77 4 7
-
 Bos taurus
3.1.1.77 4.5 5.5
-
 Homo sapiens