Any feedback?
Literature summary extracted from
- Maleylacetone cis-trans-isomerase: affinity chromatography on glutathione-bound Sepharose. Two-substrate-binding sequence from inhibition patterns (1976), Biochemistry, 15, 4228-4233.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 5.2.1.2 | GSH | the enzyme binds glutathione through the backbone of the tripeptide | Vibrio sp. |  |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 5.2.1.2 | GSSG | - |
Vibrio sp. | |
| 5.2.1.2 | S-Methylglutathione | - |
Vibrio sp. | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 5.2.1.2 | 0.14 | - |
GSH | - |
Vibrio sp. | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 5.2.1.2 | Vibrio sp. | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 5.2.1.2 | - |
Vibrio sp. |
Reaction
| EC Number | Reaction | Comment | Organism | Reaction ID |
|---|---|---|---|---|
| 5.2.1.2 | 4-Maleylacetoacetate = 4-fumarylacetoacetate | ordered sequence of binding: maleylacetone first followed by glutathione | Vibrio sp. |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 5.2.1.2 | (+/-)-2-bromo-3-(4-nitrophenyl)propionic acid + glutathione | - |
Vibrio sp. | 2-(glutathion-S-yl)-3-(4-nitrophenyl)propanoic acid | - |
? | |
| 5.2.1.2 | Maleylacetoacetate | - |
Vibrio sp. | Fumarylacetoacetate | - |
? | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
