BRENDA - Enzyme Database

Characterization of the enzymatic hydrolysis of acetate from alkylacetylglycerols in the de novo pathway of PAF biosynthesis

Blank, M.L.; Smith, Z.L.; Cress, E.A.; Snyder, F.; Biochim. Biophys. Acta 1042, 153-158 (1990) View publication on PubMed

Data extracted from this reference:

Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
3.1.1.71
NaF
10 mM
Mus musculus
KM Value [mM]
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
3.1.1.71
0.045
-
1-Hexadecyl-2-acetyl-sn-glycerol
-
Mus musculus
Localization
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
3.1.1.71
cytosol
10% of total activity
Mus musculus
5829
-
3.1.1.71
membrane
90% of total activity
Mus musculus
16020
-
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
3.1.1.71
additional information
Mus musculus
the enzyme may play an important role in regulating the levels of platelet-activating factor synthesized by the de novo pathway via hydrolysis of the immediate precursor of platelet-activating factor
?
-
-
?
Organism
EC Number
Organism
UniProt
Commentary
Textmining
3.1.1.71
Mus musculus
-
-
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
3.1.1.71
Ehrlich ascites carcinoma cell
-
Mus musculus
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Substrate Product ID
3.1.1.71
1-hexadecyl-2-acetyl-sn-glycerol
-
23590
Mus musculus
1-Hexadecyl-sn-glycerol + acetate
-
23590
Mus musculus
?
3.1.1.71
2-acetyl-1-alkyl-sn-glycerol
-
23590
Mus musculus
1-Alkyl-sn-glycerol + acetate
-
23590
Mus musculus
?
3.1.1.71
additional information
the enzyme may play an important role in regulating the levels of platelet-activating factor synthesized by the de novo pathway via hydrolysis of the immediate precursor of platelet-activating factor
23590
Mus musculus
?
-
-
-
?
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
3.1.1.71
NaF
10 mM
Mus musculus
KM Value [mM] (protein specific)
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
3.1.1.71
0.045
-
1-Hexadecyl-2-acetyl-sn-glycerol
-
Mus musculus
Localization (protein specific)
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
3.1.1.71
cytosol
10% of total activity
Mus musculus
5829
-
3.1.1.71
membrane
90% of total activity
Mus musculus
16020
-
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
3.1.1.71
additional information
Mus musculus
the enzyme may play an important role in regulating the levels of platelet-activating factor synthesized by the de novo pathway via hydrolysis of the immediate precursor of platelet-activating factor
?
-
-
?
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
3.1.1.71
Ehrlich ascites carcinoma cell
-
Mus musculus
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ID
3.1.1.71
1-hexadecyl-2-acetyl-sn-glycerol
-
23590
Mus musculus
1-Hexadecyl-sn-glycerol + acetate
-
23590
Mus musculus
?
3.1.1.71
2-acetyl-1-alkyl-sn-glycerol
-
23590
Mus musculus
1-Alkyl-sn-glycerol + acetate
-
23590
Mus musculus
?
3.1.1.71
additional information
the enzyme may play an important role in regulating the levels of platelet-activating factor synthesized by the de novo pathway via hydrolysis of the immediate precursor of platelet-activating factor
23590
Mus musculus
?
-
-
-
?