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Literature summary extracted from

  • Geren, C.R.; Geren, L.M.; Ebner, K.E.
    Inhibition and inactivation of bovine mammary and liver UDP-galactose-4-epimerase (1977), J. Biol. Chem., 252, 2089-2094.
    View publication on PubMed

General Stability

EC Number General Stability Organism
5.1.3.2 unstable in absence of mercaptoethanol or dithiothreitol Bos taurus
5.1.3.2 uridine nucleotides provide almost total protection against the apparent first order inactivation of epimerase by trypsin. NAD+ partially protects against trypsin inactivation Bos taurus

Inhibitors

EC Number Inhibitors Comment Organism Structure
5.1.3.2 2-Hydroxy-5-nitrobenzyl bromide a combination of NAD+ and UDP protects against modification Bos taurus
5.1.3.2 NADH
-
 Bos taurus
5.1.3.2 NEM
-
 Bos taurus
5.1.3.2 p-hydroxymercuribenzoate
-
 Bos taurus
5.1.3.2 Showdomycin
-
 Bos taurus

Organism

EC Number Organism UniProt Comment Textmining
5.1.3.2 Bos taurus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
5.1.3.2
-
 Bos taurus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
5.1.3.2 liver
-
 Bos taurus
-
5.1.3.2 mammary gland
-
 Bos taurus
-
5.1.3.2 thyroid gland
-
 Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.1.3.2 UDP-galactose
-
 Bos taurus UDP-glucose
-
 ?