EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.4.1.16 | (2S,5S)-2-amino-3(3-carboxy-2-isoxazolin-5-yl)propanoic acid | competitive inhibition | Lysinibacillus sphaericus | |
5.1.1.7 | additional information | none of the following compounds shows significant inhibition: (2S)-2-amino-3-(4-carboxyimidazol-1-yl)propanoic acid, (2S,5'R)-2-amino-3-(3-carboxy-2-isoxazolin-5-yl)propanoic acid and its 5'S diastereomer, 2-isoxazoline-3-carboxylic acid, and 2-isoxazoline-3,5-dicarboxylic acid | Escherichia coli |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.4.1.16 | Lysinibacillus sphaericus | - |
- |
- |
5.1.1.7 | Escherichia coli | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
5.1.1.7 | - |
Escherichia coli |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.4.1.16 | L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H | - |
Lysinibacillus sphaericus | meso-2,6-diaminoheptanedioate + H2O + NAD(P)+ | - |
r | |
5.1.1.7 | LL-2,6-Diaminoheptanedioate | - |
Escherichia coli | meso-Diaminoheptanedioate | - |
? |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.4.1.16 | NADPH | - |
Lysinibacillus sphaericus |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.4.1.16 | 0.0042 | - |
(2S,5S)-2-amino-3(3-carboxy-2-isoxazolin-5-yl)propanoic acid | competitive inhibition of L-2-amino-6-oxoheptanedioate | Lysinibacillus sphaericus | |
1.4.1.16 | 0.023 | - |
(2S,5S)-2-amino-3(3-carboxy-2-isoxazolin-5-yl)propanoic acid | noncompetitive inhibition of meso-diaminopimelate | Lysinibacillus sphaericus |