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Literature summary extracted from

  • Szamosi, I.; Shaner, D.L.; Singh, B.K.
    Identification and characterization of a biodegradative form of threonine dehydratase in senescing tomato (Lycopersicon esculentum) leaf (1993), Plant Physiol., 101, 999-1004.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.3.1.19 Ile 2 different forms: one enzyme form is sensitive to inhibition by Ile, the other form is insensitive to inhibition by Ile Solanum lycopersicum

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.3.1.19 0.25
-
 L-Thr Ile-sensitive enzyme form and Ile-insensitive form Solanum lycopersicum
4.3.1.19 0.25
-
 L-Ser Ile-insensitive enzyme form Solanum lycopersicum
4.3.1.19 1.7
-
 L-Ser Ile-sensitive form Solanum lycopersicum

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.3.1.19 200000
-
 Ile-insensitive enzyme form, gel filtration Solanum lycopersicum
4.3.1.19 370000
-
 Ile-sensitive enzyme form, gel filtration Solanum lycopersicum

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.3.1.19 L-Thr Solanum lycopersicum key enzyme in biosynthesis of Ile ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.3.1.19 Solanum lycopersicum
-
 2 different forms: one enzyme form is sensitive to inhibition by Ile, the other form is insensitive to inhibition by Ile
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.3.1.19 leaf isoleucine-sensitive enzyme form occurs predominantly in younger leaves, isoleucine-insensitive enzyme form occurs predominantly in older leaves Solanum lycopersicum
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.3.1.19 L-Ser
-
 Solanum lycopersicum pyruvate + NH3
-
 ?
4.3.1.19 L-Thr key enzyme in biosynthesis of Ile Solanum lycopersicum ?
-
 ?
4.3.1.19 L-threonine
-
 Solanum lycopersicum 2-oxobutanoate + NH3
-
 ?