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Literature summary extracted from
- Studies on extracellular proteins from Staphylococcus aureus. 3. Investigations on the heterogeneity of hyaluronate lyase using the method of isoelectric focusing (1968), Biochim. Biophys. Acta, 168, 218-227.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.2.2.1 | Cys | slight | Staphylococcus aureus |  |
| 4.2.2.1 | EDTA | slight | Staphylococcus aureus | |
| 4.2.2.1 | iodoacetate | 10 mM, complete inhibition | Staphylococcus aureus | |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 4.2.2.1 | extracellular | - |
Staphylococcus aureus | - |
- |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.2.2.1 | Staphylococcus aureus | - |
- |
- |
| 4.2.2.1 | Staphylococcus aureus M18 | - |
- |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.2.2.1 | hyaluronate | - |
Staphylococcus aureus | alpha-4-deoxy-L-threo-hex-4-enopyranosyluronic acid-beta-1,3--N-acetyl-glucosamine | - |
? | |
| 4.2.2.1 | hyaluronate | - |
Staphylococcus aureus M18 | alpha-4-deoxy-L-threo-hex-4-enopyranosyluronic acid-beta-1,3--N-acetyl-glucosamine | - |
? | |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 4.2.2.1 | 4.8 | 6 | - |
Staphylococcus aureus |
pH Range
| EC Number | pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|---|
| 4.2.2.1 | 4.6 | 7 | pH 4.6: about 75% of maximal activity, pH 7.0: about 45% of maximal activity | Staphylococcus aureus |
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