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Literature summary extracted from
- Assessment of the active-site requirements of 5-aminolevulinic acid dehydratase: evaluation of substrate and product analogues as competitive inhibitors (1992), J. Org. Chem., 57, 5005-5013.
No PubMed abstract available
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.2.1.24 | 4-nitro-2-butanone | - |
Cereibacter sphaeroides |  |
| 4.2.1.24 | 5-hydroxy-4-oxopentanoic acid | - |
Cereibacter sphaeroides | |
| 4.2.1.24 | 5-nitrilo-4-oxopentanoic acid | - |
Cereibacter sphaeroides | |
| 4.2.1.24 | rac-2-hydroxy-4-oxopentanoic acid | - |
Cereibacter sphaeroides | |
| 4.2.1.24 | rac-3-hydroxy-4-oxopentanoic acid | - |
Cereibacter sphaeroides | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.2.1.24 | Cereibacter sphaeroides | - |
- |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.2.1.24 | 5-aminolevulinate + 5-aminolevulinate | - |
Cereibacter sphaeroides | porphobilinogen + 2 H2O | - |
? | |
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Release 2023.1 (January 2023)
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