Literature summary extracted from

Yamasaki, H.; Moriyama, T.
delta-Aminolevulinic acid dehydratase of Mycobacterium phlei (1971), Biochim. Biophys. Acta, 227, 698-705.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
4.2.1.24	5-hydroxy-4-oxo-L-norvaline	competitive	Mycolicibacterium phlei
4.2.1.24	5-hydroxylevulinate	competitive	Mycolicibacterium phlei
4.2.1.24	EDTA	-	Mycolicibacterium phlei
4.2.1.24	K2SO4	slight	Mycolicibacterium phlei
4.2.1.24	levulinic acid	competitive	Mycolicibacterium phlei

KM Value [mM]

EC Number	KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
4.2.1.24	0.077	-	5-aminolevulinate	-	Mycolicibacterium phlei

Metals/Ions

EC Number	Metals/Ions	Comment	Organism	Structure
4.2.1.24	Mg2+	required	Mycolicibacterium phlei

Organism

EC Number	Organism	UniProt	Comment	Textmining
4.2.1.24	Mycolicibacterium phlei	-	-	-

Purification (Commentary)

EC Number	Purification (Comment)	Organism
4.2.1.24	-	Mycolicibacterium phlei

Specific Activity [micromol/min/mg]

EC Number	Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
4.2.1.24	additional information	-	-	Mycolicibacterium phlei

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
4.2.1.24	5-aminolevulinate + 5-aminolevulinate	-	Mycolicibacterium phlei	porphobilinogen + 2 H2O	-	?

pH Optimum

EC Number	pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
4.2.1.24	9.2	-	-	Mycolicibacterium phlei

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)