Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Loew, P.; Bussell, K.; Dawson, S.P.; Billett, M.A.; Mayer, R.J.; Reynolds, S.E.
    Expression of a 26S proteasome ATPase subunit, MS73, in muscles that undergo developmentally programmed cell death, and its control by ecdysteroid hormones in the insect Manduca sexta (1997), FEBS Lett., 400, 345-349.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
5.6.1.5 cDNA clone encoding MS73 Manduca sexta

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
5.6.1.5 47000
-
 SDS-PAGE Manduca sexta

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5.6.1.5 ATP + H2O + polypeptide Saccharomyces cerevisiae
-
 ADP + phosphate + unfolded polypeptide
-
 ?
5.6.1.5 ATP + H2O + polypeptide Manduca sexta
-
 ADP + phosphate + unfolded polypeptide
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
5.6.1.5 Manduca sexta
-
 tobacco hornworm moth
-
5.6.1.5 Saccharomyces cerevisiae
-
-
-

Reaction

EC Number Reaction Comment Organism Reaction ID
5.6.1.5 ATP + H2O + polypeptide = ADP + phosphate + unfolded polypeptide belongs to the AAA-type superfamily and, like EC 3.6.4.5, minus-end-directed kinesin ATPase, is involved in channel gating and polypeptide unfolding before proteolysis in the proteasome. Six ATPase subunits are present in the regulatory particle (RP) of 26S proteasome Saccharomyces cerevisiae
a
5.6.1.5 ATP + H2O + polypeptide = ADP + phosphate + unfolded polypeptide belongs to the AAA-type superfamily and, like EC 3.6.4.5, minus-end-directed kinesin ATPase, is involved in channel gating and polypeptide unfolding before proteolysis in the proteasome. Six ATPase subunits are present in the regulatory particle (RP) of 26S proteasome Manduca sexta
a

Source Tissue

EC Number Source Tissue Comment Organism Textmining
5.6.1.5 muscle
-
 Manduca sexta
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.6.1.5 ATP + H2O + polypeptide
-
 Saccharomyces cerevisiae ADP + phosphate + unfolded polypeptide
-
 ?
5.6.1.5 ATP + H2O + polypeptide
-
 Manduca sexta ADP + phosphate + unfolded polypeptide
-
 ?

Synonyms

EC Number Synonyms Comment Organism
5.6.1.5 26S proteasome
-
 Saccharomyces cerevisiae
5.6.1.5 26S proteasome
-
 Manduca sexta
5.6.1.5 MS73 26S proteasome subunit Manduca sexta
5.6.1.5 YTA2
-
 Saccharomyces cerevisiae