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Literature summary extracted from

  • Sablin, E.P.; Case, R.B.; Dai, S.C.; Hart, C.L.; Ruby, A.; Vale, R.D.; Fletterick, R.J.
    Direction determination in the minus-end-directed kinesin motor ncd (1998), Nature, 395, 813-816.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
5.6.1.4
-
 Drosophila melanogaster

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
5.6.1.4
-
 Drosophila melanogaster
5.6.1.4
-
 Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5.6.1.4 ATP + H2O + a kinesin associated with a microtubule at position n Drosophila melanogaster
-
 ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end)
-
 ?
5.6.1.4 ATP + H2O + a kinesin associated with a microtubule at position n Rattus norvegicus
-
 ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end)
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
5.6.1.4 Drosophila melanogaster
-
-
-
5.6.1.4 Rattus norvegicus
-
-
-

Reaction

EC Number Reaction Comment Organism Reaction ID
5.6.1.4 ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end) structurally almost identical to EC3.6.4.3 (microtubule-severing ATPase) but the movement it catalyses is towards the minus end of microtubules Drosophila melanogaster
a
5.6.1.4 ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end) structurally almost identical to EC3.6.4.3 (microtubule-severing ATPase) but the movement it catalyses is towards the minus end of microtubules Rattus norvegicus
a

Source Tissue

EC Number Source Tissue Comment Organism Textmining
5.6.1.4 brain
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.6.1.4 ATP + H2O + a kinesin associated with a microtubule at position n
-
 Drosophila melanogaster ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end)
-
 ?
5.6.1.4 ATP + H2O + a kinesin associated with a microtubule at position n
-
 Rattus norvegicus ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end)
-
 ?

Subunits

EC Number Subunits Comment Organism
5.6.1.4 dimer ncd polypeptide expressed in Escherichia coli Drosophila melanogaster

Synonyms

EC Number Synonyms Comment Organism
5.6.1.4 ncd
-
 Drosophila melanogaster