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Literature summary extracted from
- Identification and classification of 16 new kinesin superfamily (KIF) proteins in mouse genome (1997), Proc. Natl. Acad. Sci. USA, 94, 9654-9659.
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 5.6.1.3 | cDNA, PCR to identify new KIFs | Mus musculus |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 5.6.1.3 | ATP + H2O + a kinesin associated with a microtubule at position n | Mus musculus | - |
ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? |  |
| 5.6.1.3 | ATP + H2O + a kinesin associated with a microtubule at position n | Saccharomyces cerevisiae | - |
ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
| 5.6.1.3 | ATP + H2O + a kinesin associated with a microtubule at position n | Xenopus laevis | - |
ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
| 5.6.1.3 | ATP + H2O + a kinesin associated with a microtubule at position n | Caenorhabditis elegans | - |
ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
| 5.6.1.3 | GTP + H2O + a kinesin associated with a microtubule at position n | Mus musculus | - |
GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
| 5.6.1.3 | GTP + H2O + a kinesin associated with a microtubule at position n | Saccharomyces cerevisiae | - |
GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
| 5.6.1.3 | GTP + H2O + a kinesin associated with a microtubule at position n | Xenopus laevis | - |
GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
| 5.6.1.3 | GTP + H2O + a kinesin associated with a microtubule at position n | Caenorhabditis elegans | - |
GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 5.6.1.3 | Caenorhabditis elegans | - |
- |
- |
| 5.6.1.3 | Mus musculus | - |
mouse | - |
| 5.6.1.3 | Saccharomyces cerevisiae | - |
- |
- |
| 5.6.1.3 | Xenopus laevis | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 5.6.1.3 | - |
Mus musculus |
Reaction
| EC Number | Reaction | Comment | Organism | Reaction ID |
|---|---|---|---|---|
| 5.6.1.3 | ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) | microtubular motor protein, involved in organelle movement, in mitosis and meiosis. In contrast to dynein, it moves along microtubules towards the plus end. Composed of two heavy (a) chains (110kDa) and two more light (b) chains (65-75 kDa). Also hydrolyzes GTP. | Mus musculus | |
| 5.6.1.3 | ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) | microtubular motor protein, involved in organelle movement, in mitosis and meiosis. In contrast to dynein, it moves along microtubules towards the plus end. Composed of two heavy (a) chains (110kDa) and two more light (b) chains (65-75 kDa). Also hydrolyzes GTP. | Saccharomyces cerevisiae | |
| 5.6.1.3 | ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) | microtubular motor protein, involved in organelle movement, in mitosis and meiosis. In contrast to dynein, it moves along microtubules towards the plus end. Composed of two heavy (a) chains (110kDa) and two more light (b) chains (65-75 kDa). Also hydrolyzes GTP. | Xenopus laevis | |
| 5.6.1.3 | ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) | microtubular motor protein, involved in organelle movement, in mitosis and meiosis. In contrast to dynein, it moves along microtubules towards the plus end. Composed of two heavy (a) chains (110kDa) and two more light (b) chains (65-75 kDa). Also hydrolyzes GTP. | Caenorhabditis elegans |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 5.6.1.3 | brain | - |
Mus musculus | - |
| 5.6.1.3 | heart | - |
Mus musculus | - |
| 5.6.1.3 | hippocampus | - |
Mus musculus | - |
| 5.6.1.3 | intestine | - |
Mus musculus | - |
| 5.6.1.3 | kidney | - |
Mus musculus | - |
| 5.6.1.3 | lung | - |
Mus musculus | - |
| 5.6.1.3 | olfactory bulb | - |
Mus musculus | - |
| 5.6.1.3 | spleen | - |
Mus musculus | - |
| 5.6.1.3 | testis | - |
Mus musculus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 5.6.1.3 | ATP + H2O + a kinesin associated with a microtubule at position n | - |
Mus musculus | ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
| 5.6.1.3 | ATP + H2O + a kinesin associated with a microtubule at position n | - |
Saccharomyces cerevisiae | ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
| 5.6.1.3 | ATP + H2O + a kinesin associated with a microtubule at position n | - |
Xenopus laevis | ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
| 5.6.1.3 | ATP + H2O + a kinesin associated with a microtubule at position n | - |
Caenorhabditis elegans | ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
| 5.6.1.3 | GTP + H2O + a kinesin associated with a microtubule at position n | - |
Mus musculus | GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
| 5.6.1.3 | GTP + H2O + a kinesin associated with a microtubule at position n | - |
Saccharomyces cerevisiae | GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
| 5.6.1.3 | GTP + H2O + a kinesin associated with a microtubule at position n | - |
Xenopus laevis | GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
| 5.6.1.3 | GTP + H2O + a kinesin associated with a microtubule at position n | - |
Caenorhabditis elegans | GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 5.6.1.3 | CELF56E3 | - |
Caenorhabditis elegans |
| 5.6.1.3 | Eg5 | - |
Xenopus laevis |
| 5.6.1.3 | KIF10 | - |
Mus musculus |
| 5.6.1.3 | KIF11 | - |
Mus musculus |
| 5.6.1.3 | KIF13A | - |
Mus musculus |
| 5.6.1.3 | KIF13B | - |
Mus musculus |
| 5.6.1.3 | KIF15 | - |
Mus musculus |
| 5.6.1.3 | KIF16A | - |
Mus musculus |
| 5.6.1.3 | KIF16B | - |
Mus musculus |
| 5.6.1.3 | KIF1A | - |
Mus musculus |
| 5.6.1.3 | KIF1B | - |
Mus musculus |
| 5.6.1.3 | KIF3A | - |
Mus musculus |
| 5.6.1.3 | KIF3B | - |
Mus musculus |
| 5.6.1.3 | KIF5 | - |
Mus musculus |
| 5.6.1.3 | KIF5A | - |
Mus musculus |
| 5.6.1.3 | KIF5B | - |
Mus musculus |
| 5.6.1.3 | KIF5C | - |
Mus musculus |
| 5.6.1.3 | KIF6 | - |
Mus musculus |
| 5.6.1.3 | KIF7 | - |
Mus musculus |
| 5.6.1.3 | KIF8 | - |
Mus musculus |
| 5.6.1.3 | KIFC2 | - |
Mus musculus |
| 5.6.1.3 | KIP1 | - |
Saccharomyces cerevisiae |
| 5.6.1.3 | nKHC | - |
Mus musculus |
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