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Literature summary extracted from

  • O'Brien, M.C.; McKay, D.B.
    How potassium affects the activity of the molecular chaperone Hsc70 I. Potassium is required for optimal ATPase activity (1995), J. Biol. Chem., 270, 2247-2250.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.6.4.10 0.0005
-
 ATP in presence of KCl Bos taurus
3.6.4.10 0.025
-
 ATP
-
 Bos taurus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.6.4.10 K+ Hsc70 Escherichia coli
3.6.4.10 Rb+ activates to half the turnover rate observed with K+ Escherichia coli

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.6.4.10 44000
-
 ATPase domain of Hsc70 Bos taurus
3.6.4.10 70000
-
-
 Escherichia coli
3.6.4.10 70000
-
-
 Bos taurus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.6.4.10 ATP + H2O Escherichia coli
-
 ADP + phosphate
-
 ?
3.6.4.10 ATP + H2O Bos taurus
-
 ADP + phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.6.4.10 Bos taurus
-
-
-
3.6.4.10 Escherichia coli
-
-
-

Reaction

EC Number Reaction Comment Organism Reaction ID
3.6.4.10 ATP + H2O = ADP + phosphate highly diverse group of enzymes that perform many functions that are similar to those of chaperonins. They comprise a number of heat-shock-cognate proteins. They are also active in clathrin uncoating and in the oligomerization of actin Escherichia coli
a
3.6.4.10 ATP + H2O = ADP + phosphate highly diverse group of enzymes that perform many functions that are similar to those of chaperonins. They comprise a number of heat-shock-cognate proteins. They are also active in clathrin uncoating and in the oligomerization of actin Bos taurus
a

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.6.4.10 ATP + H2O
-
 Escherichia coli ADP + phosphate
-
 ?
3.6.4.10 ATP + H2O
-
 Bos taurus ADP + phosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.6.4.10 heat shock cognate protein
-
 Escherichia coli
3.6.4.10 heat shock cognate protein
-
 Bos taurus
3.6.4.10 Hsc70
-
 Bos taurus