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Literature summary extracted from

  • Carafoli, E.
    The Ca2+ pump of the plasma membrane (1992), J. Biol. Chem., 267, 2115-2118.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
7.2.2.10 Calmodulin activates Homo sapiens
7.2.2.10 Calmodulin activates Rattus norvegicus
7.2.2.10 Calmodulin activates Bos taurus

Inhibitors

EC Number Inhibitors Comment Organism Structure
7.2.2.10 La3+
-
 Bos taurus
7.2.2.10 La3+
-
 Homo sapiens
7.2.2.10 La3+
-
 Rattus norvegicus
7.2.2.10 vanadate
-
 Bos taurus
7.2.2.10 vanadate
-
 Homo sapiens
7.2.2.10 vanadate
-
 Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
7.2.2.10 Bos taurus
-
 enzyme isoform PMCA 5
-
7.2.2.10 Homo sapiens
-
 enzyme isoforms PMCA 1, PMCA 2, PMCA 4
-
7.2.2.10 Rattus norvegicus
-
 enzyme isoform PMCA 1, PMCA 2 and PMCA3
-

Reaction

EC Number Reaction Comment Organism Reaction ID
7.2.2.10 ATP + H2O + Ca2+[side 1] = ADP + phosphate + Ca2+[side 2] formation of a phosphorylated intermediate Homo sapiens
a
7.2.2.10 ATP + H2O + Ca2+[side 1] = ADP + phosphate + Ca2+[side 2] formation of a phosphorylated intermediate Rattus norvegicus
a
7.2.2.10 ATP + H2O + Ca2+[side 1] = ADP + phosphate + Ca2+[side 2] formation of a phosphorylated intermediate Bos taurus
a

Source Tissue

EC Number Source Tissue Comment Organism Textmining
7.2.2.10 erythrocyte
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
7.2.2.10 ATP + H2O + Ca2+/out
-
 Homo sapiens ADP + phosphate + Ca2+/in
-
 ?
7.2.2.10 ATP + H2O + Ca2+/out
-
 Rattus norvegicus ADP + phosphate + Ca2+/in
-
 ?
7.2.2.10 ATP + H2O + Ca2+/out
-
 Bos taurus ADP + phosphate + Ca2+/in
-
 ?