Literature summary extracted from

Tusnady, G.E.; Bakos, E.; Varadi, A.; Sarkadi, B.
Membrane topology distinguishes a subfamily of the ATP-binding cassette (ABC) transporters (1997), FEBS Lett., 402, 1-3.

Organism

EC Number	Organism	UniProt	Comment	Textmining
5.6.1.6	Homo sapiens	-	-	-

Posttranslational Modification

EC Number	Posttranslational Modification	Comment	Organism
5.6.1.6	glycoprotein	-	Homo sapiens

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
5.6.1.6	ATP + H2O + closed Cl- channel	chloride channel	Homo sapiens	ADP + phosphate + open Cl- channel	-	?

Subunits

EC Number	Subunits	Comment	Organism
5.6.1.6	More	enzyme of the ABC transporter family	Homo sapiens
5.6.1.6	More	the enzyme contains a tandem repeat of six transmembrane helices, each set followed by an ATP-binding domain, an additional, large, N-terminal hydrophobic region contains 4-6 transmembrane helices, is occasionally glycosylated on the cell surface and may play a key role in interactions with anionic compounds	Homo sapiens

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Release 2023.1 (January 2023)