Literature summary extracted from

Naren, A.P.; Quick, M.W.; Collawn, J.F.; Nelson, D.J.; Kirk, K.L.
Syntaxin 1A inhibits CFTR chloride channels by means of domain-specific protein-protein interactions (1998), Proc. Natl. Acad. Sci. USA, 95, 10972-10977.

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
5.6.1.6	expression in Xenopus oocytes	Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
5.6.1.6	ATP + H2O + closed Cl- channel	Homo sapiens	syntaxin 1A limits the functional activities of normal and disease-associated forms of the chloride channel	ADP + phosphate + open Cl- channel	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
5.6.1.6	Homo sapiens	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
5.6.1.6	ATP + H2O + closed Cl- channel	chloride channel	Homo sapiens	ADP + phosphate + open Cl- channel	-	?
5.6.1.6	ATP + H2O + closed Cl- channel	syntaxin 1A limits the functional activities of normal and disease-associated forms of the chloride channel	Homo sapiens	ADP + phosphate + open Cl- channel	-	?

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Release 2023.1 (January 2023)