EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
7.6.2.2 | 0.0053 | - |
leukotriene C4/in | - |
Homo sapiens | |
7.6.2.2 | 0.0057 | - |
2,4-dinitrophenyl S-glutathione/in | - |
Homo sapiens | |
7.6.2.2 | 0.0256 | - |
estradiol 17-beta-D-glucuronide/in | - |
Homo sapiens | |
7.6.2.2 | 0.248 | - |
glycocholate/in | - |
Homo sapiens | |
7.6.2.2 | 0.776 | - |
methotrexate/in | - |
Homo sapiens |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
7.6.2.2 | additional information | Homo sapiens | MRP3 is competent in the transport of glutathione S-conjugates, glucuronides and methotrexate, the enzyme is active in the transport of monoanionic human bile constituent glycocholate | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
7.6.2.2 | Homo sapiens | - |
MRP3 | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
7.6.2.2 | 2,4-dinitrophenyl S-glutathione/in + ATP + H2O | - |
Homo sapiens | 2,4-dinitrophenyl S-glutathione/out + ADP + H2O | - |
? | |
7.6.2.2 | estradiol 17-beta-D-glucuronide/in + ATP + H2O | - |
Homo sapiens | estradiol 17-beta-D-glucuronide/out + ADP + phosphate | - |
? | |
7.6.2.2 | glycocholate/in + ATP + H2O | - |
Homo sapiens | glycocholate/out + ADP + phosphate | - |
? | |
7.6.2.2 | leukotriene C4/in + ATP + H2O | - |
Homo sapiens | leukotriene C4/out + ADP + phosphate | - |
? | |
7.6.2.2 | methotrexate/in + ATP + H2O | - |
Homo sapiens | methotrexate/out + ADP + phosphate | - |
? | |
7.6.2.2 | additional information | MRP3 is competent in the transport of glutathione S-conjugates, glucuronides and methotrexate, the enzyme is active in the transport of monoanionic human bile constituent glycocholate | Homo sapiens | ? | - |
? |