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Literature summary extracted from

  • Futai, M.; Kanazawa, H.
    Structure and function of proton-translocating adenosine triphosphatase (F0F1): Biochemical and molecular biological approaches (1983), Microbiol. Rev., 47, 285-312.
    View publication on PubMedView publication on EuropePMC

Protein Variants

EC Number Protein Variants Comment Organism
7.1.2.2 additional information mutation of the subunits alpha, beta, gamma and delta and epsilon, mutations of the F0 subunit Escherichia coli

Inhibitors

EC Number Inhibitors Comment Organism Structure
7.1.2.2 N,N'-dicyclohexylcarbodiimide
-
 Bacillus sp. PS3
7.1.2.2 N,N'-dicyclohexylcarbodiimide
-
 Bos taurus
7.1.2.2 N,N'-dicyclohexylcarbodiimide
-
 Escherichia coli
7.1.2.2 N,N'-dicyclohexylcarbodiimide
-
 Saccharomyces cerevisiae

Organism

EC Number Organism UniProt Comment Textmining
7.1.2.2 Bacillus sp. PS3
-
-
-
7.1.2.2 Bos taurus
-
-
-
7.1.2.2 Escherichia coli
-
-
-
7.1.2.2 Mus musculus
-
-
-
7.1.2.2 Saccharomyces cerevisiae
-
-
-
7.1.2.2 Spinacia oleracea
-
-
-
7.1.2.2 Zea mays
-
-
-

Reaction

EC Number Reaction Comment Organism Reaction ID
7.1.2.2 ATP + H2O + 4 H+[side 1] = ADP + phosphate + 4 H+[side 2] mechanism of proton conduction through F0, and the catalytic mechanism of F1 Escherichia coli
a

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
7.1.2.2 ATP + H2O + H+/in
-
 Mus musculus ADP + phosphate + H+/out
-
 ?
7.1.2.2 ATP + H2O + H+/in
-
 Escherichia coli ADP + phosphate + H+/out
-
 ?
7.1.2.2 ATP + H2O + H+/in
-
 Saccharomyces cerevisiae ADP + phosphate + H+/out
-
 ?
7.1.2.2 ATP + H2O + H+/in
-
 Bos taurus ADP + phosphate + H+/out
-
 ?
7.1.2.2 ATP + H2O + H+/in
-
 Spinacia oleracea ADP + phosphate + H+/out
-
 ?
7.1.2.2 ATP + H2O + H+/in
-
 Zea mays ADP + phosphate + H+/out
-
 ?
7.1.2.2 ATP + H2O + H+/in
-
 Bacillus sp. PS3 ADP + phosphate + H+/out
-
 ?

Subunits

EC Number Subunits Comment Organism
7.1.2.2 ?
-
 Escherichia coli
7.1.2.2 ?
-
 Bos taurus
7.1.2.2 ?
-
 Spinacia oleracea
7.1.2.2 More
-
 Saccharomyces cerevisiae
7.1.2.2 More
-
 Bos taurus
7.1.2.2 More x * F1alpha, 55259 + x * F1beta, 50117, + x * F1gamma, 19303, + x * F1epsilon, 14914, + x * F0a, 30275, + x * F0b, 17244, + x * F0c, 8246 Escherichia coli