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Literature summary extracted from
- Mechanism of enzymatic hydrolysis of adenosinetriphosphate (1953), J. Biol. Chem., 202, 217-226.
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.6.1.8 | Ca2+ | - |
Rattus norvegicus |  |
| 3.6.1.8 | Ca2+ | no effect | Bos taurus | |
| 3.6.1.8 | Mg2+ | - |
Rattus norvegicus | |
| 3.6.1.8 | Mg2+ | no effect | Bos taurus | |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.6.1.8 | ATP + H2O | Rattus norvegicus | - |
AMP + diphosphate | - |
? | |
| 3.6.1.8 | ATP + H2O | Bos taurus | - |
AMP + diphosphate | - |
? | |
| 3.6.1.8 | ATP + H2O | Oryctolagus cuniculus | - |
AMP + diphosphate | - |
? | |
| 3.6.1.8 | ATP + H2O | Crotalus adamanteus | - |
AMP + diphosphate | - |
? | |
| 3.6.1.8 | ITP + H2O | Crotalus adamanteus | - |
IMP + diphosphate | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.6.1.8 | Bos taurus | - |
- |
- |
| 3.6.1.8 | Crotalus adamanteus | - |
snake | - |
| 3.6.1.8 | Oryctolagus cuniculus | - |
- |
- |
| 3.6.1.8 | Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.6.1.8 | partial purification | Bos taurus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.6.1.8 | kidney | - |
Rattus norvegicus | - |
| 3.6.1.8 | plasma | - |
Bos taurus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.6.1.8 | ATP + H2O | - |
Rattus norvegicus | AMP + diphosphate | - |
? | |
| 3.6.1.8 | ATP + H2O | - |
Bos taurus | AMP + diphosphate | - |
? | |
| 3.6.1.8 | ATP + H2O | - |
Oryctolagus cuniculus | AMP + diphosphate | - |
? | |
| 3.6.1.8 | ATP + H2O | - |
Crotalus adamanteus | AMP + diphosphate | - |
? | |
| 3.6.1.8 | ITP + H2O | - |
Crotalus adamanteus | IMP + diphosphate | - |
? | |
Temperature Stability [°C]
| EC Number | Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 3.6.1.8 | 60 | - |
30 min at 60°C causes no loss of activity | Bos taurus |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.6.1.8 | 8.4 | 9 | - |
Bos taurus |
pH Range
| EC Number | pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.6.1.8 | 6 | 10 | 20% activity at pH 6, 50% activity at pH 10 | Bos taurus |
| 3.6.1.8 | 7.4 | 8.8 | much higher activity at pH 8.8 | Crotalus adamanteus |
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Release 2023.1 (January 2023)
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