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Literature summary extracted from

  • Fujimori, K.; Ohta, D.
    Isolation and characterization of a histidine biosynthetic gene in Arabidopsis encoding a polypeptide with two separate domains for phosphoribosyl-ATP pyrophosphohydrolase and phosphoribosyl-AMP cyclohydrolase (1998), Plant Physiol., 118, 275-283.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.5.4.19 expression in Escherichia coli Arabidopsis thaliana
3.6.1.31 in Escherichia coli Arabidopsis sp.

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.6.1.31 31670
-
 calculated from amino acid sequence Arabidopsis sp.

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.5.4.19 1-(5-phosphoribosyl)-AMP + H2O Arabidopsis thaliana
-
 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide
-
 ?
3.6.1.31 N-1-(5'-phosphoribosyl)-ATP + H2O Arabidopsis sp. enzyme of histidine biosynthesis pathway N-1-(5'-phosphoribosyl)-AMP + diphosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.5.4.19 Arabidopsis thaliana O82768 ecotype Columbia
-
3.6.1.31 Arabidopsis sp.
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.5.4.19 seed
-
 Arabidopsis thaliana
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.5.4.19 1-(5-phosphoribosyl)-AMP + H2O
-
 Arabidopsis thaliana 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide
-
 ?
3.6.1.31 N-1-(5'-phosphoribosyl)-ATP + H2O
-
 Arabidopsis sp. N-1-(5'-phosphoribosyl)-AMP + diphosphate
-
 ?
3.6.1.31 N-1-(5'-phosphoribosyl)-ATP + H2O enzyme of histidine biosynthesis pathway Arabidopsis sp. N-1-(5'-phosphoribosyl)-AMP + diphosphate
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.5.4.19 30
-
 assays at 30°C Arabidopsis thaliana