BRENDA - Enzyme Database

The glutamyl-tRNA synthetase of Escherichia coli contains one atom of zinc essential for its native conformation and its catalytic activity

Liu, J.; Lin, S.X.; Blochet, J.E.; Pezolet, M.; Lapointe, J.; Biochemistry 32, 11390-11396 (1993)

Data extracted from this reference:

Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
6.1.1.17
1,10-phenanthroline
ATP protects the enzyme against zinc removal
Escherichia coli
Metals/Ions
EC Number
Metals/Ions
Commentary
Organism
Structure
6.1.1.17
Zinc
zinc metalloenzyme
Bacillus subtilis
6.1.1.17
Zinc
enzyme contains one zinc atom strongly bound, which is essential for its native conformation and its catalytic acitivity; zinc metalloenzyme
Escherichia coli
6.1.1.17
Zinc
enzyme does not contain zinc
Thermus thermophilus
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
6.1.1.17
Bacillus subtilis
-
-
-
6.1.1.17
Escherichia coli
-
-
-
6.1.1.17
Thermus thermophilus
-
wild-type and mutant enzymes
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
6.1.1.17
ATP + L-glutamate + tRNAGlu
-
210
Bacillus subtilis
AMP + diphosphate + L-glutamyl-tRNAGlu
-
210
Bacillus subtilis
-
6.1.1.17
ATP + L-glutamate + tRNAGlu
-
210
Thermus thermophilus
AMP + diphosphate + L-glutamyl-tRNAGlu
-
210
Thermus thermophilus
-
6.1.1.17
ATP + L-glutamate + tRNAGlu
-
210
Escherichia coli
AMP + diphosphate + L-glutamyl-tRNAGlu
-
210
Escherichia coli
-
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
6.1.1.17
1,10-phenanthroline
ATP protects the enzyme against zinc removal
Escherichia coli
Metals/Ions (protein specific)
EC Number
Metals/Ions
Commentary
Organism
Structure
6.1.1.17
Zinc
zinc metalloenzyme
Bacillus subtilis
6.1.1.17
Zinc
enzyme contains one zinc atom strongly bound, which is essential for its native conformation and its catalytic acitivity; zinc metalloenzyme
Escherichia coli
6.1.1.17
Zinc
enzyme does not contain zinc
Thermus thermophilus
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
6.1.1.17
ATP + L-glutamate + tRNAGlu
-
210
Bacillus subtilis
AMP + diphosphate + L-glutamyl-tRNAGlu
-
210
Bacillus subtilis
-
6.1.1.17
ATP + L-glutamate + tRNAGlu
-
210
Thermus thermophilus
AMP + diphosphate + L-glutamyl-tRNAGlu
-
210
Thermus thermophilus
-
6.1.1.17
ATP + L-glutamate + tRNAGlu
-
210
Escherichia coli
AMP + diphosphate + L-glutamyl-tRNAGlu
-
210
Escherichia coli
-