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Literature summary extracted from

  • McIntosh, E.M.; Ager, D.D.; Gadsen, M.H.; Haynes, R.H.
    Human dUTP pyrophosphatase: cDNA sequence and potential biological importance of the enzyme (1992), Proc. Natl. Acad. Sci. USA, 89, 8020-8024.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.6.1.23 isolation of cDNA clones and characterization Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.6.1.23 16600
-
 x * 16600, calculation from nucleotide sequence Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.6.1.23 dUTP + H2O Homo sapiens the enzyme may generally perform an essential role in DNA replication and therefore can serve as a target enzyme for the development of chemotherapeutic compounds ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.6.1.23 Homo sapiens
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.6.1.23 dUTP + H2O
-
 Homo sapiens dUMP + diphosphate
-
 ?
3.6.1.23 dUTP + H2O the enzyme may generally perform an essential role in DNA replication and therefore can serve as a target enzyme for the development of chemotherapeutic compounds Homo sapiens ?
-
 ?

Subunits

EC Number Subunits Comment Organism
3.6.1.23 ? x * 16600, calculation from nucleotide sequence Homo sapiens