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Literature summary extracted from
- Drosophila deoxyuridine triphosphatase. Purification and characterization (1987), J. Biol. Chem., 262, 130-134.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.6.1.23 | 1,10-phenanthroline | - |
Drosophila melanogaster |  |
| 3.6.1.23 | Ca2+ | - |
Drosophila melanogaster | |
| 3.6.1.23 | EDTA | - |
Drosophila melanogaster | |
| 3.6.1.23 | EGTA | - |
Drosophila melanogaster | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.6.1.23 | 0.001 | - |
dUTP | - |
Drosophila melanogaster | |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.6.1.23 | Mg2+ | 0.5 mM, stimulates by 7% | Drosophila melanogaster | |
| 3.6.1.23 | Mg2+ | metalloenzyme, may contain Mg2+, Mn2+ or both | Drosophila melanogaster | |
| 3.6.1.23 | Mn2+ | metalloenzyme, may contain Mg2+, Mn2+ or both | Drosophila melanogaster | |
| 3.6.1.23 | Zn2+ | 0.5 mM, stimulates by 7% | Drosophila melanogaster | |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.6.1.23 | 46000 | - |
gel filtration, glycerol density gradient sedimentation | Drosophila melanogaster |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.6.1.23 | Drosophila melanogaster | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.6.1.23 | - |
Drosophila melanogaster |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.6.1.23 | embryo | embryos respresenting the only step in the life cycle of Drosophila with clearly detectable levels of the enzyme | Drosophila melanogaster | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 3.6.1.23 | additional information | - |
- |
Drosophila melanogaster |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.6.1.23 | dUTP + H2O | - |
Drosophila melanogaster | dUMP + diphosphate | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 3.6.1.23 | dimer | 1 * 45000-50000, SDS-PAGE | Drosophila melanogaster |
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