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Literature summary extracted from

  • Vallejo, C.G.; Lobaton, C.D.; Quintanilla, M.; Sillero, A.; Sillero, M.A.G.
    Dinucleosidasetetraphosphatase in rat liver and Artemia salina (1976), Biochim. Biophys. Acta, 438, 304-309.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.6.1.17 adenosine 5'-tetraphosphate Ki in nanomolar range Artemia salina
3.6.1.17 adenosine 5'-tetraphosphate Ki in nanomolar range Rattus norvegicus
3.6.1.17 ADP
-
Artemia salina
3.6.1.17 ADP
-
Rattus norvegicus
3.6.1.17 AMP
-
Artemia salina
3.6.1.17 AMP
-
Rattus norvegicus
3.6.1.17 ATP
-
Artemia salina
3.6.1.17 ATP
-
Rattus norvegicus
3.6.1.17 GDP
-
Artemia salina
3.6.1.17 GDP
-
Rattus norvegicus
3.6.1.17 GMP
-
Artemia salina
3.6.1.17 GMP
-
Rattus norvegicus
3.6.1.17 GTP
-
Artemia salina
3.6.1.17 GTP
-
Rattus norvegicus
3.6.1.17 guanosine 5'-tetraphosphate Ki in nanomolar range Artemia salina
3.6.1.17 guanosine 5'-tetraphosphate Ki in nanomolar range Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.6.1.17 0.002
-
P1,P4-bis(5'-adenosyl) tetraphosphate
-
Rattus norvegicus
3.6.1.17 0.002
-
P1,P4-bis(5'-guanosyl) tetraphosphate
-
Rattus norvegicus
3.6.1.17 0.002
-
P1,P4-bis(5'-guanosyl) tetraphosphate
-
Artemia salina
3.6.1.17 0.005
-
P1,P4-bis(5'-guanosyl) tetraphosphate
-
Artemia salina
3.6.1.17 0.01
-
P1,P4-bis(5'-uridyl) tetraphosphate
-
Rattus norvegicus
3.6.1.17 0.011
-
P1,P4-bis(5'-uridyl) tetraphosphate
-
Artemia salina
3.6.1.17 0.016
-
P1,P4-bis(5'-xanthosyl) tetraphosphate
-
Rattus norvegicus
3.6.1.17 0.018
-
P1,P4-bis(5'-xanthosyl) tetraphosphate
-
Artemia salina

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.6.1.17 17500
-
gel filtration Artemia salina
3.6.1.17 21000
-
gel filtration Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.6.1.17 P1,P4-bis(5'-adenosyl) tetraphosphate + H2O Rattus norvegicus
-
ATP + AMP
-
?
3.6.1.17 P1,P4-bis(5'-adenosyl) tetraphosphate + H2O Artemia salina
-
ATP + AMP
-
?
3.6.1.17 P1,P4-bis(5'-guanosyl)tetraphosphate + H2O Rattus norvegicus
-
GTP + GMP
-
?
3.6.1.17 P1,P4-bis(5'-guanosyl)tetraphosphate + H2O Artemia salina
-
GTP + GMP
-
?

Organism

EC Number Organism UniProt Comment Textmining
3.6.1.17 Artemia salina
-
brine shrimp
-
3.6.1.17 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.6.1.17 liver
-
Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.6.1.17 P1,P4-bis(5'-adenosyl) tetraphosphate + H2O
-
Rattus norvegicus ATP + AMP
-
?
3.6.1.17 P1,P4-bis(5'-adenosyl) tetraphosphate + H2O
-
Artemia salina ATP + AMP
-
?
3.6.1.17 P1,P4-bis(5'-guanosyl)tetraphosphate + H2O
-
Rattus norvegicus GTP + GMP
-
?
3.6.1.17 P1,P4-bis(5'-guanosyl)tetraphosphate + H2O
-
Artemia salina GTP + GMP
-
?
3.6.1.17 P1,P4-bis(5'-uridyl) tetraphosphate + H2O
-
Rattus norvegicus UTP + UMP
-
?
3.6.1.17 P1,P4-bis(5'-uridyl) tetraphosphate + H2O
-
Artemia salina UTP + UMP
-
?
3.6.1.17 P1,P4-bis(5'-xanthosyl) tetraphosphate + H2O
-
Rattus norvegicus XTP + XMP
-
?
3.6.1.17 P1,P4-bis(5'-xanthosyl) tetraphosphate + H2O
-
Artemia salina XTP + XMP
-
?

pH Stability

EC Number pH Stability pH Stability Maximum Comment Organism
3.6.1.17 4.1
-
no loss of activity within 4 h, 25% loss of activity within 24 h Artemia salina
3.6.1.17 4.1
-
95% loss of activity within 1 min Rattus norvegicus