BRENDA - Enzyme Database

Dinucleosidasetetraphosphatase in rat liver and Artemia salina

Vallejo, C.G.; Lobaton, C.D.; Quintanilla, M.; Sillero, A.; Sillero, M.A.G.; Biochim. Biophys. Acta 438, 304-309 (1976)

Data extracted from this reference:

Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
3.6.1.17
adenosine 5'-tetraphosphate
Ki in nanomolar range
Artemia salina
3.6.1.17
adenosine 5'-tetraphosphate
Ki in nanomolar range
Rattus norvegicus
3.6.1.17
ADP
-
Artemia salina
3.6.1.17
ADP
-
Rattus norvegicus
3.6.1.17
AMP
-
Artemia salina
3.6.1.17
AMP
-
Rattus norvegicus
3.6.1.17
ATP
-
Artemia salina
3.6.1.17
ATP
-
Rattus norvegicus
3.6.1.17
GDP
-
Artemia salina
3.6.1.17
GDP
-
Rattus norvegicus
3.6.1.17
GMP
-
Artemia salina
3.6.1.17
GMP
-
Rattus norvegicus
3.6.1.17
GTP
-
Artemia salina
3.6.1.17
GTP
-
Rattus norvegicus
3.6.1.17
guanosine 5'-tetraphosphate
Ki in nanomolar range
Artemia salina
3.6.1.17
guanosine 5'-tetraphosphate
Ki in nanomolar range
Rattus norvegicus
KM Value [mM]
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
3.6.1.17
0.002
-
P1,P4-bis(5'-adenosyl) tetraphosphate
-
Rattus norvegicus
3.6.1.17
0.002
-
P1,P4-bis(5'-guanosyl) tetraphosphate
-
Artemia salina
3.6.1.17
0.002
-
P1,P4-bis(5'-guanosyl) tetraphosphate
-
Rattus norvegicus
3.6.1.17
0.005
-
P1,P4-bis(5'-guanosyl) tetraphosphate
-
Artemia salina
3.6.1.17
0.01
-
P1,P4-bis(5'-uridyl) tetraphosphate
-
Rattus norvegicus
3.6.1.17
0.011
-
P1,P4-bis(5'-uridyl) tetraphosphate
-
Artemia salina
3.6.1.17
0.016
-
P1,P4-bis(5'-xanthosyl) tetraphosphate
-
Rattus norvegicus
3.6.1.17
0.018
-
P1,P4-bis(5'-xanthosyl) tetraphosphate
-
Artemia salina
Molecular Weight [Da]
EC Number
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
3.6.1.17
17500
-
gel filtration
Artemia salina
3.6.1.17
21000
-
gel filtration
Rattus norvegicus
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
3.6.1.17
P1,P4-bis(5'-adenosyl) tetraphosphate + H2O
Rattus norvegicus
-
ATP + AMP
-
Rattus norvegicus
?
3.6.1.17
P1,P4-bis(5'-adenosyl) tetraphosphate + H2O
Artemia salina
-
ATP + AMP
-
Artemia salina
?
3.6.1.17
P1,P4-bis(5'-guanosyl)tetraphosphate + H2O
Rattus norvegicus
-
GTP + GMP
-
Rattus norvegicus
?
3.6.1.17
P1,P4-bis(5'-guanosyl)tetraphosphate + H2O
Artemia salina
-
GTP + GMP
-
Artemia salina
?
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
3.6.1.17
Artemia salina
-
brine shrimp
-
3.6.1.17
Rattus norvegicus
-
-
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
3.6.1.17
liver
-
Rattus norvegicus
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.6.1.17
P1,P4-bis(5'-adenosyl) tetraphosphate + H2O
-
209896
Rattus norvegicus
ATP + AMP
-
209896
Rattus norvegicus
?
3.6.1.17
P1,P4-bis(5'-adenosyl) tetraphosphate + H2O
-
209896
Artemia salina
ATP + AMP
-
209896
Artemia salina
?
3.6.1.17
P1,P4-bis(5'-guanosyl)tetraphosphate + H2O
-
209896
Rattus norvegicus
GTP + GMP
-
209896
Rattus norvegicus
?
3.6.1.17
P1,P4-bis(5'-guanosyl)tetraphosphate + H2O
-
209896
Artemia salina
GTP + GMP
-
209896
Artemia salina
?
3.6.1.17
P1,P4-bis(5'-uridyl) tetraphosphate + H2O
-
209896
Rattus norvegicus
UTP + UMP
-
209896
Rattus norvegicus
?
3.6.1.17
P1,P4-bis(5'-uridyl) tetraphosphate + H2O
-
209896
Artemia salina
UTP + UMP
-
209896
Artemia salina
?
3.6.1.17
P1,P4-bis(5'-xanthosyl) tetraphosphate + H2O
-
209896
Rattus norvegicus
XTP + XMP
-
209896
Rattus norvegicus
?
3.6.1.17
P1,P4-bis(5'-xanthosyl) tetraphosphate + H2O
-
209896
Artemia salina
XTP + XMP
-
209896
Artemia salina
?
pH Stability
EC Number
pH Stability
pH Stability Maximum
Commentary
Organism
3.6.1.17
4.1
-
no loss of activity within 4 h, 25% loss of activity within 24 h
Artemia salina
3.6.1.17
4.1
-
95% loss of activity within 1 min
Rattus norvegicus
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
3.6.1.17
adenosine 5'-tetraphosphate
Ki in nanomolar range
Artemia salina
3.6.1.17
adenosine 5'-tetraphosphate
Ki in nanomolar range
Rattus norvegicus
3.6.1.17
ADP
-
Artemia salina
3.6.1.17
ADP
-
Rattus norvegicus
3.6.1.17
AMP
-
Artemia salina
3.6.1.17
AMP
-
Rattus norvegicus
3.6.1.17
ATP
-
Artemia salina
3.6.1.17
ATP
-
Rattus norvegicus
3.6.1.17
GDP
-
Artemia salina
3.6.1.17
GDP
-
Rattus norvegicus
3.6.1.17
GMP
-
Artemia salina
3.6.1.17
GMP
-
Rattus norvegicus
3.6.1.17
GTP
-
Artemia salina
3.6.1.17
GTP
-
Rattus norvegicus
3.6.1.17
guanosine 5'-tetraphosphate
Ki in nanomolar range
Artemia salina
3.6.1.17
guanosine 5'-tetraphosphate
Ki in nanomolar range
Rattus norvegicus
KM Value [mM] (protein specific)
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
3.6.1.17
0.002
-
P1,P4-bis(5'-adenosyl) tetraphosphate
-
Rattus norvegicus
3.6.1.17
0.002
-
P1,P4-bis(5'-guanosyl) tetraphosphate
-
Artemia salina
3.6.1.17
0.002
-
P1,P4-bis(5'-guanosyl) tetraphosphate
-
Rattus norvegicus
3.6.1.17
0.005
-
P1,P4-bis(5'-guanosyl) tetraphosphate
-
Artemia salina
3.6.1.17
0.01
-
P1,P4-bis(5'-uridyl) tetraphosphate
-
Rattus norvegicus
3.6.1.17
0.011
-
P1,P4-bis(5'-uridyl) tetraphosphate
-
Artemia salina
3.6.1.17
0.016
-
P1,P4-bis(5'-xanthosyl) tetraphosphate
-
Rattus norvegicus
3.6.1.17
0.018
-
P1,P4-bis(5'-xanthosyl) tetraphosphate
-
Artemia salina
Molecular Weight [Da] (protein specific)
EC Number
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
3.6.1.17
17500
-
gel filtration
Artemia salina
3.6.1.17
21000
-
gel filtration
Rattus norvegicus
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
3.6.1.17
P1,P4-bis(5'-adenosyl) tetraphosphate + H2O
Rattus norvegicus
-
ATP + AMP
-
Rattus norvegicus
?
3.6.1.17
P1,P4-bis(5'-adenosyl) tetraphosphate + H2O
Artemia salina
-
ATP + AMP
-
Artemia salina
?
3.6.1.17
P1,P4-bis(5'-guanosyl)tetraphosphate + H2O
Rattus norvegicus
-
GTP + GMP
-
Rattus norvegicus
?
3.6.1.17
P1,P4-bis(5'-guanosyl)tetraphosphate + H2O
Artemia salina
-
GTP + GMP
-
Artemia salina
?
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
3.6.1.17
liver
-
Rattus norvegicus
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.6.1.17
P1,P4-bis(5'-adenosyl) tetraphosphate + H2O
-
209896
Rattus norvegicus
ATP + AMP
-
209896
Rattus norvegicus
?
3.6.1.17
P1,P4-bis(5'-adenosyl) tetraphosphate + H2O
-
209896
Artemia salina
ATP + AMP
-
209896
Artemia salina
?
3.6.1.17
P1,P4-bis(5'-guanosyl)tetraphosphate + H2O
-
209896
Rattus norvegicus
GTP + GMP
-
209896
Rattus norvegicus
?
3.6.1.17
P1,P4-bis(5'-guanosyl)tetraphosphate + H2O
-
209896
Artemia salina
GTP + GMP
-
209896
Artemia salina
?
3.6.1.17
P1,P4-bis(5'-uridyl) tetraphosphate + H2O
-
209896
Rattus norvegicus
UTP + UMP
-
209896
Rattus norvegicus
?
3.6.1.17
P1,P4-bis(5'-uridyl) tetraphosphate + H2O
-
209896
Artemia salina
UTP + UMP
-
209896
Artemia salina
?
3.6.1.17
P1,P4-bis(5'-xanthosyl) tetraphosphate + H2O
-
209896
Rattus norvegicus
XTP + XMP
-
209896
Rattus norvegicus
?
3.6.1.17
P1,P4-bis(5'-xanthosyl) tetraphosphate + H2O
-
209896
Artemia salina
XTP + XMP
-
209896
Artemia salina
?
pH Stability (protein specific)
EC Number
pH Stability
pH Stability Maximum
Commentary
Organism
3.6.1.17
4.1
-
no loss of activity within 4 h, 25% loss of activity within 24 h
Artemia salina
3.6.1.17
4.1
-
95% loss of activity within 1 min
Rattus norvegicus