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Literature summary extracted from

  • Vallejo, C.G.; Sillero, M.A.G.; Sillero, A.
    Diguanosinetetraphosphate guanosylhydrolase in Artemia salina (1974), Biochim. Biophys. Acta, 358, 117-125.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.6.1.17 adenosine 5'-tetraphosphate Ki in nanomolar range Artemia salina
3.6.1.17 ATP competitive Artemia salina
3.6.1.17 GDP competitive Artemia salina
3.6.1.17 GMP competitive Artemia salina
3.6.1.17 GTP competitive Artemia salina
3.6.1.17 guanosine 5'-tetraphosphate Ki in nanomolar range Artemia salina

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.6.1.17 0.005
-
 P1,P4-bis(5'-guanosyl) tetraphosphate
-
 Artemia salina

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.6.1.17 cytosol
-
 Artemia salina 5829
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.6.1.17 P1,P4-bis(5'-guanosyl)tetraphosphate + H2O Artemia salina
-
 GTP + GMP
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.6.1.17 Artemia salina
-
 brine shrimp
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.6.1.17 partial Artemia salina

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.6.1.17 0.0015
-
 crude extract Artemia salina
3.6.1.17 0.023
-
 partially purified enzyme Artemia salina

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.6.1.17 P1,P4-bis(5'-guanosyl)tetraphosphate + H2O
-
 Artemia salina GTP + GMP
-
 ?