Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Kim, J.S.; Kim, W.Y.; Rho, H.W.; Park, J.W.; Park, B.H.; Han, M.K.; Kim, U.H.; Kim, H.R.
    Purification and characterization of adenosine diphosphate ribose pyrophosphatase from human erythrocytes (1998), Int. J. Biochem. Cell Biol., 30, 629-638.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.6.1.13 ADP potent noncompetitive inhibitor Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.6.1.13 0.169
-
 ADPribose
-
 Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.6.1.13 34000
-
 2 * 34000, SDS-PAGE with and without mercaptoethanol Homo sapiens
3.6.1.13 68000
-
 gel filtration Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.6.1.13 ADPribose + H2O Homo sapiens the enzyme may play an important role in the regulation of intracellular steady-state of free ADPribose AMP + D-ribose 5-phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.6.1.13 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.6.1.13
-
 Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.6.1.13 8.59
-
-
 Homo sapiens

Storage Stability

EC Number Storage Stability Organism
3.6.1.13 -20°C, no loss of activity after months Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.6.1.13 ADP-glucose + H2O at 21% of the activity with ADPribose Homo sapiens AMP + alpha-D-glucose 1-phosphate
-
 ?
3.6.1.13 ADP-mannose + H2O at 70% of the activity with ADPribose Homo sapiens AMP + D-mannose 1-phosphate
-
 ?
3.6.1.13 ADPribose + H2O
-
 Homo sapiens AMP + D-ribose 5-phosphate
-
 ?
3.6.1.13 ADPribose + H2O the enzyme may play an important role in the regulation of intracellular steady-state of free ADPribose Homo sapiens AMP + D-ribose 5-phosphate
-
 ?
3.6.1.13 CDP-glucose + H2O at 5% of the activity with ADPribose Homo sapiens CMP + glucose 5-phosphate
-
 ?
3.6.1.13 GDP-mannose + H2O at 40% of the activity with ADPribose Homo sapiens GMP + D-mannose 1-phosphate
-
 ?
3.6.1.13 IDP-ribose + H2O at 59% of the activity with ADPribose Homo sapiens IMP + ribose 5-phosphate
-
 ?
3.6.1.13 UDP-glucose + H2O at 5% of the activity with ADPribose Homo sapiens UMP + glucose 5-phosphate
-
 ?
3.6.1.13 UDP-mannose + H2O at 20% of the activity with ADPribose Homo sapiens UMP + D-mannose 1-phosphate
-
 ?

Subunits

EC Number Subunits Comment Organism
3.6.1.13 dimer 2 * 34000, SDS-PAGE with and without mercaptoethanol Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.6.1.13 9.5
-
-
 Homo sapiens