EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.6.1.1 | diphosphate | hydrolysis of imidophosphate competitively inhibited in the absence of divalent cations | Bos taurus | |
3.6.1.1 | p-chloromercuriphenyl sulfonate | 50% inhibition of hydrolysis of diphosphate at 25 µM | Bos taurus |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.6.1.1 | 0.12 | - |
Imidodiphosphate | - |
Bos taurus | |
3.6.1.1 | 0.14 | - |
diphosphate | - |
Bos taurus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
3.6.1.1 | cytosol | - |
Bos taurus | 5829 | - |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
3.6.1.1 | Co2+ | increases hydrolysis of imidophosphate | Bos taurus | |
3.6.1.1 | Mg2+ | increases hydrolysis of imidophosphate | Bos taurus | |
3.6.1.1 | Mg2+ | or other divalent cation required for hydrolysis of diphosphate | Bos taurus | |
3.6.1.1 | Mn2+ | increases hydrolysis of imidophosphate | Bos taurus |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
3.6.1.1 | 33000 | - |
2 * 33000, SDS-PAGE | Bos taurus |
3.6.1.1 | 56000 | - |
ultracentrifuge method | Bos taurus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.6.1.1 | diphosphate + H2O | Bos taurus | - |
2 phosphate | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.6.1.1 | Bos taurus | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
3.6.1.1 | - |
Bos taurus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.6.1.1 | liver | - |
Bos taurus | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
3.6.1.1 | 2.1 | - |
diphosphate | Bos taurus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.6.1.1 | diphosphate + H2O | - |
Bos taurus | 2 phosphate | - |
? | |
3.6.1.1 | imidodiphosphate + 2 H2O | hydrolysis even in the absence of divalent cations | Bos taurus | 2 phosphate + NH3 | - |
ir |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
3.6.1.1 | dimer | 2 * 33000, SDS-PAGE | Bos taurus |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
3.6.1.1 | 30 | - |
- |
Bos taurus |
EC Number | Temperature Minimum [°C] | Temperature Maximum [°C] | Comment | Organism |
---|---|---|---|---|
3.6.1.1 | 30 | 65 | - |
Bos taurus |
EC Number | Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|---|
3.6.1.1 | 70 | - |
no activity | Bos taurus |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
3.6.1.1 | 6 | 7 | - |
Bos taurus |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.6.1.1 | 0.025 | - |
p-chloromercuriphenyl sulfonate | - |
Bos taurus |