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Literature summary extracted from

  • Almatawah, Q.A.; Cowan, D.A.
    Thermostable nitrilase catalysed production of nicotinic acid from 3-cyanopyridine (1999), Enzyme Microb. Technol., 25, 718-724.
No PubMed abstract available

General Stability

EC Number General Stability Organism
3.5.5.1 more resistant to thermal inactivation if cells immobilized in calcium alginate beads, stabilizing effect of 3-cyanopyridine Aeribacillus pallidus

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.5.5.1 3-Cyanopyridine inhibition at concentrations greater than 0.2 M Aeribacillus pallidus
3.5.5.1 nicotinic acid inhibition at concentrations greater than 0.2 M Aeribacillus pallidus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.5.5.1 3-cyanopyridine + 2 H2O Aeribacillus pallidus
-
 nicotinic acid + NH3
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.5.5.1 Aeribacillus pallidus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.5.5.1 cell culture best inducer of enzyme formation: benzonitrile Aeribacillus pallidus
-

Storage Stability

EC Number Storage Stability Organism
3.5.5.1 -80°C, 0.1 M potassium phosphate, pH 7.0, 5 mM EDTA, stored as packed cells, no loss of activity Aeribacillus pallidus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.5.5.1 3-cyanopyridine + 2 H2O
-
 Aeribacillus pallidus nicotinic acid + NH3
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.5.5.1 3-cyanopyridinase
-
 Aeribacillus pallidus

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.5.5.1 60
-
-
 Aeribacillus pallidus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.5.5.1 8
-
-
 Aeribacillus pallidus