BRENDA - Enzyme Database show

Inhibition of Escherichia coli cytidine deaminase by a phosphopyrimidine nucleoside

Ashley, G.W.; Bartlett, P.A.; J. Biol. Chem. 259, 13621-13627 (1984)

Data extracted from this reference:

Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
3.5.4.5
3,4,5,6-Tetrahydrouridine
potent competitive inhibitor
Escherichia coli
3.5.4.5
3,4,5,6-Tetrahydrouridine
potent competitive inhibitor
Homo sapiens
3.5.4.5
phosphapyrimidine nucleoside
-
Escherichia coli
Molecular Weight [Da]
EC Number
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
3.5.4.5
54000
-
-
Escherichia coli
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
3.5.4.5
cytidine + H2O
Escherichia coli
-
uridine + NH3
-
-
?
3.5.4.5
cytidine + H2O
Homo sapiens
-
uridine + NH3
-
-
?
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
3.5.4.5
Escherichia coli
-
-
-
3.5.4.5
Homo sapiens
-
HeLa cells; human
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
3.5.4.5
liver
-
Homo sapiens
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.5.4.5
2'-deoxycytidine + H2O
-
209654
Escherichia coli
2'-deoxyuridine + NH3
-
-
-
?
3.5.4.5
2'-deoxycytidine + H2O
-
209654
Homo sapiens
2'-deoxyuridine + NH3
-
-
-
?
3.5.4.5
cytidine + H2O
-
209654
Escherichia coli
uridine + NH3
-
-
-
?
3.5.4.5
cytidine + H2O
-
209654
Homo sapiens
uridine + NH3
-
-
-
?
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
3.5.4.5
3,4,5,6-Tetrahydrouridine
potent competitive inhibitor
Escherichia coli
3.5.4.5
3,4,5,6-Tetrahydrouridine
potent competitive inhibitor
Homo sapiens
3.5.4.5
phosphapyrimidine nucleoside
-
Escherichia coli
Molecular Weight [Da] (protein specific)
EC Number
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
3.5.4.5
54000
-
-
Escherichia coli
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
3.5.4.5
cytidine + H2O
Escherichia coli
-
uridine + NH3
-
-
?
3.5.4.5
cytidine + H2O
Homo sapiens
-
uridine + NH3
-
-
?
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
3.5.4.5
liver
-
Homo sapiens
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.5.4.5
2'-deoxycytidine + H2O
-
209654
Escherichia coli
2'-deoxyuridine + NH3
-
-
-
?
3.5.4.5
2'-deoxycytidine + H2O
-
209654
Homo sapiens
2'-deoxyuridine + NH3
-
-
-
?
3.5.4.5
cytidine + H2O
-
209654
Escherichia coli
uridine + NH3
-
-
-
?
3.5.4.5
cytidine + H2O
-
209654
Homo sapiens
uridine + NH3
-
-
-
?