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Literature summary extracted from

  • Akedo, H.; Nishihara, H.; Shinkai, K.; Komatsu, K.; Ishikawa, S.
    Multiple forms of human adenosine deaminase. 1. Purification and characterization of two molecular species (1972), Biochim. Biophys. Acta, 276, 257-271.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.5.4.4 2-Aminopurine
-
 Homo sapiens
3.5.4.4 adenine
-
 Homo sapiens
3.5.4.4 Cu2+
-
 Homo sapiens
3.5.4.4 guanosine
-
 Homo sapiens
3.5.4.4 Hg2+
-
 Homo sapiens
3.5.4.4 Inosine
-
 Homo sapiens
3.5.4.4 p-chloromercuryphenylsulfonate
-
 Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.5.4.4 0.066
-
 adenosine El Homo sapiens
3.5.4.4 0.074
-
 adenosine Es Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.5.4.4 47000
-
 Es, gel filtration Homo sapiens
3.5.4.4 230000
-
 El, gel filtration Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.5.4.4 Homo sapiens
-
 normal B-cells and T-cell lines MOLT-4
-
3.5.4.4 Homo sapiens
-
 RPMI-8402
-
3.5.4.4 Homo sapiens
-
 CCRF-CEM
-
3.5.4.4 Homo sapiens
-
 larger enzyme: El, smaller enzyme: Es
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.5.4.4
-
 Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.5.4.4 liver
-
 Homo sapiens
-
3.5.4.4 lung
-
 Homo sapiens
-
3.5.4.4 stomach
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.5.4.4 2.7
-
 El Homo sapiens
3.5.4.4 17.4
-
 Es Homo sapiens

Storage Stability

EC Number Storage Stability Organism
3.5.4.4 0°C, phosphate buffer, pH 7.0, 2-mercaptoethanol, 1 month, enzyme EI Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.5.4.4 2'-deoxyadenosine + H2O
-
 Homo sapiens 2'-deoxyinosine + NH3
-
 ?
3.5.4.4 adenosine + H2O
-
 Homo sapiens inosine + NH3
-
 ?

Subunits

EC Number Subunits Comment Organism
3.5.4.4 polymer
-
 Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.5.4.4 7
-
-
 Homo sapiens