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Literature summary extracted from
- Occurrence of GTP cyclohydrolase I in Bacillus stearothermophilus (1979), J. Biochem., 86, 1679-1685.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.5.4.16 | Ca2+ | - |
Geobacillus stearothermophilus |  |
| 3.5.4.16 | Cd2+ | - |
Geobacillus stearothermophilus | |
| 3.5.4.16 | Cu2+ | - |
Geobacillus stearothermophilus | |
| 3.5.4.16 | Hg2+ | - |
Geobacillus stearothermophilus | |
| 3.5.4.16 | Pb2+ | - |
Geobacillus stearothermophilus | |
| 3.5.4.16 | Sn2+ | - |
Geobacillus stearothermophilus | |
| 3.5.4.16 | Sr2+ | - |
Geobacillus stearothermophilus | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.5.4.16 | 980 | - |
GTP | - |
Geobacillus stearothermophilus | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.5.4.16 | Geobacillus stearothermophilus | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.5.4.16 | - |
Geobacillus stearothermophilus |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 3.5.4.16 | additional information | - |
- |
Geobacillus stearothermophilus |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.5.4.16 | GTP + H2O | - |
Geobacillus stearothermophilus | formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate | - |
? | |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 3.5.4.16 | 60 | 65 | - |
Geobacillus stearothermophilus |
Temperature Range [°C]
| EC Number | Temperature Minimum [°C] | Temperature Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 3.5.4.16 | 38 | 78 | half-maximal activity at | Geobacillus stearothermophilus |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.5.4.16 | 8 | 8.4 | - |
Geobacillus stearothermophilus |
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Release 2023.1 (January 2023)
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