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Literature summary extracted from
- 5-Oxoprolinase from rat kidney, I assay, purification, and determination of kinetic parameters (1975), Hoppe-Seyler's Z. Physiol. Chem., 356, 873-880.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.5.2.9 | imidazolone carboxylate | - |
Rattus norvegicus |  |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.5.2.9 | 0.0316 | - |
5-oxoproline | - |
Rattus norvegicus | |
| 3.5.2.9 | 0.1727 | - |
MgATP2- | - |
Rattus norvegicus | |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.5.2.9 | 5-oxo-L-proline + H2O + ATP | Mus musculus | - |
L-glutamate + ADP + phosphate | - |
? | |
| 3.5.2.9 | 5-oxo-L-proline + H2O + ATP | Rattus norvegicus | - |
L-glutamate + ADP + phosphate | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.5.2.9 | Mus musculus | - |
- |
- |
| 3.5.2.9 | Rattus norvegicus | - |
rat | - |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.5.2.9 | choroid plexus | - |
Mus musculus | - |
| 3.5.2.9 | choroid plexus | - |
Rattus norvegicus | - |
| 3.5.2.9 | ciliary body | - |
Rattus norvegicus | - |
| 3.5.2.9 | kidney | - |
Mus musculus | - |
| 3.5.2.9 | kidney | - |
Rattus norvegicus | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 3.5.2.9 | 0.122 | - |
- |
Rattus norvegicus |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.5.2.9 | 5-oxo-L-proline + H2O + ATP | - |
Mus musculus | L-glutamate + ADP + phosphate | - |
? | |
| 3.5.2.9 | 5-oxo-L-proline + H2O + ATP | - |
Rattus norvegicus | L-glutamate + ADP + phosphate | - |
? | |
| 3.5.2.9 | MgATP2- + H2O | - |
Rattus norvegicus | ? | - |
? | |
Turnover Number [1/s]
| EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.5.2.9 | 0.117 | - |
5-oxo-L-proline | - |
Rattus norvegicus | |
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