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Literature summary extracted from

  • Conolly, A.K.; Waley, S.G.
    Characterization of the membrane beta-lactamase in Bacillus cereus 569/H/9 (1983), Biochemistry, 22, 4647-4651.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.5.2.6 6-beta-bromopenicillanic acid
-
 Bacillus cereus
3.5.2.6 6-chloropenicillanic acid
-
 Bacillus cereus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.5.2.6 0.18
-
 benzylpenicillin beta-lactamase III Bacillus cereus
3.5.2.6 0.5
-
 ampicillin beta-lactamase III Bacillus cereus
3.5.2.6 2
-
 Methicillin beta-lactamase III Bacillus cereus
3.5.2.6 9.5
-
 cephaloridine beta-lactamase III Bacillus cereus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.5.2.6 30000
-
 beta-lactamase I, SDS-PAGE Bacillus cereus
3.5.2.6 31500
-
 beta-lactamase III, SDS-PAGE Bacillus cereus

Organism

EC Number Organism UniProt Comment Textmining
3.5.2.6 Bacillus cereus
-
-
-
3.5.2.6 Bacillus cereus 569/H/9
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.5.2.6
-
 Bacillus cereus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.5.2.6 ampicillin + H2O beta-lactamase III Bacillus cereus (2R,4S)-2-[(R)-[[(2R)-2-amino-2-phenylacetyl]amino](carboxy)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid
-
 ?
3.5.2.6 ampicillin + H2O beta-lactamase III Bacillus cereus 569/H/9 (2R,4S)-2-[(R)-[[(2R)-2-amino-2-phenylacetyl]amino](carboxy)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid
-
 ?
3.5.2.6 benzylpenicillin + H2O beta-lactamase III Bacillus cereus (2R,4S)-2-[(R)-carboxy(2-phenylacetamido)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid
-
 ?
3.5.2.6 benzylpenicillin + H2O beta-lactamase III Bacillus cereus 569/H/9 (2R,4S)-2-[(R)-carboxy(2-phenylacetamido)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid
-
 ?
3.5.2.6 cephaloridine + H2O beta-lactamase III Bacillus cereus (2R)-2-[(R)-carboxy[(thiophen-2-ylacetyl)amino]methyl]-5-(pyridinium-1-ylmethyl)-3,6-dihydro-2H-1,3-thiazine-4-carboxylate
-
 ?
3.5.2.6 cephaloridine + H2O beta-lactamase III Bacillus cereus 569/H/9 (2R)-2-[(R)-carboxy[(thiophen-2-ylacetyl)amino]methyl]-5-(pyridinium-1-ylmethyl)-3,6-dihydro-2H-1,3-thiazine-4-carboxylate
-
 ?
3.5.2.6 methicillin + H2O beta-lactamase III Bacillus cereus (2R,4S)-2-[(R)-carboxy(2,6-dimethoxybenzamido)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid
-
 ?
3.5.2.6 methicillin + H2O beta-lactamase III Bacillus cereus 569/H/9 (2R,4S)-2-[(R)-carboxy(2,6-dimethoxybenzamido)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.5.2.6 beta-lactamase I-III different in molecular weight, localization, metal ion requirement Bacillus cereus